New patch aims to turn energy-storing fats into energy-burning fats

A new approach to reducing bulging tummy fats has shown promise in laboratory trials. It combines a new way to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat.

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The body's own bathroom scales: New understanding of obesity

Researchers have found evidence for the existence of an internal body weight sensing system. This system operates like bathroom scales, registering body weight and thereby fat mass. More knowledge about the sensing mechanism could lead to a better understanding of the causes of obesity as well as new anti-obesity drugs.

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Impact of obesity on bone marrow cells

New research explores the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells). Conducted largely in genetic models of obese mice, the study shows obesity causes durable and harmful changes to the hematopoietic stem cell compartment - the blood-making factory in our bodies.

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Analysis of new studies including 250,000 people confirms sugar-sweetened drinks are linked to overweight and obesity in children and adults

A new review of the latest evidence on sugar-sweetened beverages (SSBs)- which includes 30 new studies published between 2013 and 2015 (and none of them industry sponsored) -- concludes that SSB consumption is associated with overweight and obesity, and that countries that have not already done so should take action to reduce the consumption of the so-called 'empty calories' that these drinks contain.

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PSA from your gut microbes: Enjoy the holidays, but don't forget your fiber

Anyone watching their waistline this holiday season may want to pay attention to what their gut bacteria are eating. It's not just calories that matter in a healthy diet -- it's fiber, which can influence weight gain, blood sugar, insulin sensitivity, and colon health. Research with mice help shed light on how and why fiber has such a powerful effect on the entire body.

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Health benefits of swapping animal proteins for plant proteins

Substituting one to two servings of animal proteins with plant proteins every day could lead to a small reduction in the three main cholesterol markers for cardiovascular disease prevention, a new study suggests.

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Diet rich in apples and tomatoes may help repair lungs of ex-smokers, study suggests

The natural decline in lung function over a 10-year period was slower among former smokers with a diet high in tomatoes and fruits, especially apples, suggesting certain components in these foods might help restore lung damage caused by smoking.

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Whole eggs better for muscle building and repair than egg whites

People who consume 18 grams of protein from whole eggs or from egg whites after engaging in resistance exercise differ dramatically in how their muscles build protein, a process called protein synthesis, during the post-workout period, researchers report in a new study. Specifically, the post-workout muscle-building response in those eating whole eggs is 40 percent greater than in those consuming an equivalent amount of protein from egg whites, the team found.

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FDA Proposes New Policy to Target Certain Homeopathic Drugs

FDA proposes new policy targeting unapproved homeopathic products with the greatest potential to harm people.

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Struggling to get your kids to eat healthy? 'Don't give up!' researchers say

Varied diets and persistence in exposing infants and children to healthy foods, even when they don't like them at first, are key to promoting healthy eating behaviors, a new review paper has concluded.

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Reversibility of genetic nervous system disease revealed by scientists

After developing a mouse model of Friedrich's ataxia that shows symptoms similar to patients, researchers have found that many early symptoms of the disease are completely reversible when the genetic defect linked to the ataxia is reversed.

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6 Things To Know About Complementary Health Approaches for Seasonal Affective Disorder

Seasonal Affective Disorder (SAD) is a type of depression that comes and goes with the seasons, typically starting in the late fall and early winter and going away during the spring and summer. To be diagnosed with SAD, people must meet full criteria for major depression coinciding with specific seasons (appearing in the winter or summer months) for at least 2 years. Symptoms of the winter pattern of SAD include having low energy, hypersomnia, overeating, weight gain, craving for carbohydrates, social withdrawal (feel like “hibernating”).

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Complementary Health Approaches for Seasonal Affective Disorder

Seasonal Affective Disorder (SAD), a type of depression that comes and goes with the seasons, typically starts in the late fall and early winter and goes away during the spring and summer. Depressive episodes linked to the summer can occur, but are much less common than winter episodes of SAD. To be diagnosed with SAD, people must meet full criteria for major depression coinciding with specific seasons for at least 2 years. Some of the symptoms of the winter pattern of SAD include having low energy, overeating, craving carbohydrates, and social withdrawal.

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Obesity can add five weeks of asthma symptoms per year in preschoolers

Asthma affects almost 1 in 10 children in the US and is a leading cause of emergency room visits and hospitalizations in preschoolers. According to new research, symptoms may be worse for children ages 2 to 5 who are overweight.

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What Is Gene Therapy? How Does It Work?

Gene therapy is the process of replacing defective genes with healthy ones, adding new genes to help the body fight or treat disease, or deactivating problem genes. It holds the promise to transform medicine and create options for patients who are living with difficult, and even incurable, diseases. Learn how this innovative therapy works.

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Erectile dysfunction is red flag for silent early cardiovascular disease

Despite decades long prevention and treatment efforts, cardiovascular (CV) disease continues to be the leading cause of death worldwide. Early detection of CV disease can allow for interventions to prevent heart attack and stroke, including smoking cessation, medications such as a statins, blood pressure control, weight management, exercise, and improved diet. A new study focuses on a novel risk factor for cardiovascular disease that rarely receives attention -- erectile dysfunction.

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Healthy eating linked to kids' happiness

Healthy eating is associated with better self-esteem and fewer emotional and peer problems, such as having fewer friends or being picked on or bullied, in children regardless of body weight, according to a new study. Inversely, better self-esteem is associated with better adherence to healthy eating guidelines.

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Your mood depends on the food you eat, and what you should eat changes as you get older

Diet and dietary practices differentially affect mental health in young adults versus older adults, according to new research.

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Lactic acid bacteria can protect against influenza a virus

Lactic acid bacteria, commonly used as probiotics to improve digestive health, can offer protection against different subtypes of influenza A virus, resulting in reduced weight loss after virus infection and lower amounts of virus replication in the lungs, according to a new study.

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Anti-stress compound reduces obesity and diabetes

For the first time, scientists could demonstrate that a stress protein found in muscle has a diabetes promoting effect. This finding could pave the way to a completely new treatment approach.

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FTC Sending Refund Checks Totaling More Than $8 Million to Consumers Who Bought Deceptively Marketed Weight-loss Supplements

FTC mails refund checks to people who bought weight-loss supplements that were deceptively marketed using illegal spam email, baseless weight-loss claims, and fake celebrity endorsements.

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Supplement Sellers Settle FTC, State of Maine False Advertising Charges

Health Research Laboratories settle FTC and Maine charges company deceived consumers about products.

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Keep Your Dogs and Cats Safe From Holiday Hazards

From tinsel to table scraps, holiday hazards for pets abound. Here are some tips to help you keep them safe.

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Preventing colon polyps: Another reason to lose those holiday pounds

Being over ideal body weight has known risks with respect to heart and blood pressure problems, but the list is growing. Now researchers have studied nearly 3000 patients undergoing routine physicals over a 6-year period, and found a link between weight and colon polyps.

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Genes may 'snowball' obesity, researchers find

37 genes that are well established as modulating the body mass in 75,230 adults with European ancestry have been examined by researchers, who found nine that have a "snowball effect."

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Canola oil linked to worsened memory and learning ability in Alzheimer's

Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study links canola oil consumption in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimer's disease. It's the first study to suggest that canola oil is more harmful than healthful for the brain.

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'Obesity paradox' not found when measuring new cases of cardiovascular disease

Although obesity is a well-known risk factor for getting cardiovascular disease, a controversial body of research suggests that obesity may actually be associated with improved survival among people who have cardiovascular disease. However, a new study finds that the 'obesity paradox' is not present among people with new cases of cardiovascular disease.

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Hello From NCCIH's New Leadership Team

Hello from NCCIH’s new leadership team! In this message, Acting Director David Shurtleff and Acting Deputy Director Wendy Weber introduce themselves and highlight NCCIH’s research interests and resources.

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Can diet help reduce disability, symptoms of MS?

For people with multiple sclerosis (MS), eating a healthy diet of fruits, vegetables and whole grains may be linked to having less disability and fewer symptoms than people whose diet is less healthy, according to a study.

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Cold and Flu: Prevention, Symptoms, Treatments

In much of the Northern Hemisphere, this is prime time for colds, influenza (flu), and other respiratory illnesses. While contagious viruses are active year-round, most infections occur in the fall and winter.

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Traffic pollution putting unborn babies' health at risk, warn experts

Air pollution from road traffic is having a detrimental impact upon babies' health in London, before they are born, finds a study.

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‘Safe’ tanners who use sprays and lotions less likely to get tattoos and piercings than frequent sunbathers and tanning bed users

People who often sunbathe or use tanning beds are more likely to try risky weight-loss methods and have cosmetic surgery, as well as get tattoos and piercings. But while people who seldom tan also may try unsafe diets and cosmetic surgery, they rarely opt for tattoos or piercings, according to a new study.

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How a nationally recommended diet can improve the environment

Changing your diet can improve both your health and the environment. A new study shows that European dietary recommendations on reducing animal products can reduce environmental impacts in most high-income nations.

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Study Identifies a Novel Mechanism by Which Cells May Detect a Variety of Sensations

Study build on earlier NCCIH-funded research on the Piezo2 protein and Piezo2 gene (the gene guides the production of different forms of the protein, which may play roles in distinguishing sensations).

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Binge eating linked to weight-loss challenges

Overweight or obese patients who binge eat while trying to lose weight drop half as much as those who don't binge eat or those who do and subsequently stop, according to researchers.

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Weight management program can put type 2 diabetes into remission

Type 2 diabetes can be reversed following an intensive weight management program, according a randomized trial in adults who have had the condition for up to 6 years. Almost half of participants achieved and maintained diabetes remission at one year without antidiabetic medications.

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Obesity prevented in mice fed high-fat diet

Researchers activated the Hedgehog protein pathway in the fat cells of mice. After eight weeks of eating a high-fat diet, mice that had been engineered with genes to activate the pathway didn't gain weight, but control animals whose Hedgehog pathways were not activated became obese.

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Exercise changes gut microbial composition independent of diet, team reports

Two studies -- one in mice and the other in human subjects -- offer the first definitive evidence that exercise alone can change the composition of microbes in the gut. The studies were designed to isolate exercise-induced changes from other factors -- such as diet or antibiotic use -- that might alter the intestinal microbiota.

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Call for workers to rise up

A new study has found nearly three quarters of office workers believe there is a negative relationship between sitting down all day at work and their health -- and that bosses are crucial to helping solve the problem.

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Diet success may depend on your DNA

We can add one more thing to the list of traits affected by genetics: how our bodies respond to a particular diet. Research in animal models with different genetics shows that one diet really doesn't fit all, and what works for some may not be best for others, according to a new study.

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Type 1 diabetes as common in adults as children, but many adults misdiagnosed

Type 1 diabetes is not predominantly a 'disease of childhood' as previously believed, but is similarly prevalent in adults, new research shows.

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Weight loss and risk of death: Rheumatoid arthritis findings may have wider implications

Results suggest that the findings from previous studies regarding lower weight being associated with higher mortality may not be directly related to RA and instead reflect a more generalized phenomenon.

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