How 'Dry January' is the secret to better sleep, saving money and losing weight

New research shows that taking part in Dry January sees people regaining control of their drinking, having more energy, better skin and losing weight. They also report drinking less months later.

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Proportion of cancers associated with excess body weight varies considerably by state

A new study finds an at least 1.5-fold difference in the share of cancers related to obesity between states with the highest and lowest proportions.

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Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Consumption of processed foods high in sugar and fat increase levels of advanced glycation end products (AGEs). Researchers report that AGE levels are higher in patients with estrogen receptor (ER)-positive than ER-negative breast cancer. Addition of AGEs caused breast cancer cells, whose growth had previously been controlled by tamoxifen, to begin to grow again. This suggests that patients with high AGEs may be less likely to respond to tamoxifen treatment.

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How exercise reduces belly fat in humans

Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report.

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How skin ages, loses fat and immunity

Some dermal fibroblasts can convert into fat cells that reside under the dermis, giving skin a youthful look and producing peptides that fight infections. Researchers show how this happens and what causes it to stop as people age.

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Massage May Provide Short-Term Improvement of Knee Osteoarthritis Symptoms

NCCIH-funded research suggests weekly massage therapy may reduce joint pain and improve function in people with knee osteoarthritis.

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Statins are more effective for those who follow the Mediterranean diet

For those who have already had a heart attack or a stroke, the combination of statins and Mediterranean Diet appears to be the most effective choice to reduce the risk of mortality, especially from cardiovascular causes.

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HEAL Initiative Offers New Funding Options for Clinical Trial Research on Pain

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Impact of diet intervention on autoimmunity in mice

Could a change in diet be beneficial to people with autoimmune diseases such as lupus? Researchers have revealed how a dietary intervention can help prevent the development of this autoimmune disease in susceptible mice.

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Twofold overweight risk for five-year-olds given milk cereal drinks in infancy

In five-year-old children, the risk for overweight is almost twice as high if they at 12 months had consumed milk cereal drinks every day, a study in the journal Acta Paediatrica shows.

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Nutrients in blood linked to better brain connectivity, cognition in older adults

A new study links higher levels of several key nutrients in the blood with more efficient brain connectivity and performance on cognitive tests in older adults.

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High sodium intake may contribute to increased heart-disease deaths in China

Nearly a fifth of cardiovascular disease deaths among adults in a northern province of China in 2011 may be attributed to the blood pressure-raising effect of high-sodium diets. An initiative to reduce dietary sodium intake in the region suggested thousands of deaths may be averted with reduced sodium intake.

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Birthweight and early pregnancy body mass index may risk pregnancy complications

Women who were born with a low birthweight are at increased risk of pregnancy complications, according to a new study.

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Food insecurity linked with binge-eating disorder and obesity

Food insecurity -- difficulty affording enough food to support regular, balanced meals -- was associated with increased likelihoods of binge-eating disorder and obesity in a recent study.

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New NIH BACPAC Funding Opportunities for Research on Low-Back Pain

In this blog post, NCCIH director Dr. Helene Langevin discusses funding opportunities offered by the NIH’s Back Pain Research Consortium (NIH BACPAC), part of the NIH HEAL (Helping to End Addiction Long-term) Initiative.

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Removing sweets from checkouts linked to dramatic fall in unhealthy snack purchases

Policies aimed at removing sweets and chips from checkouts could lead to a dramatic reduction to the amount of unhealthy food purchased to eat 'on the go' and a significant reduction in that purchased to take home, suggests new research.

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MRI effective for monitoring liver fat in obese patients

MRI provides a safe, noninvasive way to monitor liver fat levels in people who undergo weight loss treatments for obesity, according to a new study.

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Tiny implantable device short-circuits hunger pangs, aids weight loss

New battery-free, easily implantable weight-loss devices developed by engineers could offer a promising new weapon for battling the bulge.

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Changes in agriculture could cut sector non-CO2 greenhouse gas emissions by up to 50 percent

The agricultural sector is the world's largest source of non-CO2 greenhouse gas emissions, and research has found that changing agricultural practices and a shift in diet away from meat and dairy products could reduce the sector's emissions by up to 50 percent by 2050 compared to a situation without mitigation efforts.

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Species at the extremes of the food chain evolve faster, study says

Reef fish species at the extremes of the food chain -- those that are strict herbivores or strict fish predators -- evolve faster than fish species in the middle of the food chain with a more varied diet, according to a new study.

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New RNA sequencing strategy provides insight into microbiomes

Scientists have demonstrated the application of high-throughput transfer RNA sequencing to gut microbiome samples from mice that were fed either a low-fat or high-fat diet.

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To Eat or Not to Eat: Decorative Products on Foods Can Be Unsafe

FDA knows that some non-edible decorative glitters and dusts are promoted for use on foods. But consumers need to be aware that these materials, in fact, may contain materials that should not be eaten. Here’s how to tell if such materials are edible or not.

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CRISPR joins battle of the bulge, fights obesity without edits to genome

A weighty new study shows that CRISPR therapies can cut fat without cutting DNA. Researchers describe how a modified version of CRISPR was used to ramp up the activity of certain genes and prevent severe obesity in mice with genetic mutations that predispose them to extreme weight gain. Importantly, the researchers achieved long-lasting weight control without making a single edit to the genome.

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Large restaurant portions a global problem, study finds

A multi-country study finds that large portion sizes in fast food and full service restaurants is not a problem unique to the US. The researchers found that 94 percent of full service meals and 72 percent of fast food meals studied in five countries contained 600 calories or more.

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Excess body weight responsible for nearly 4 percent of cancers worldwide

Excess body weight accounted for approximately 3.9 percent of all cancers worldwide in 2012, a figure that is expected to rise in the coming decades given current trends.

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Spilling the Beans: How Much Caffeine is Too Much?

In what foods is caffeine found? Can caffeine pose a danger to your health? This Consumer Update answers these and other key questions about caffeine.

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Your weight history may predict your heart failure risk

In a medical records analysis of information gathered on more than 6,000 people, researchers conclude that simply asking older adult patients about their weight history at ages 20 and 40 could provide real value to clinicians in their efforts to predict patients' future risk of heart failure, heart attacks or strokes.

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Fighting obesity: Could it be as plain as dirt?

It costs the global economy an estimated US $2 trillion annually and has been dubbed a modern day health epidemic, but new research has unearthed a possible cure for obesity -- and it is as plain as dirt!

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New review of scientific studies confirms food cravings can be reduced

Food craving, the intense desire to eat certain foods, can sabotage efforts to maintain healthy eating habits and body weight, no matter the time of year. However, an examination of 28 current peer-reviewed scientific studies largely substantiates findings that changes in diet, prescription medications, physical activity and bariatric surgery reduce craving.

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BMI is a good measure of health after all, new study finds

A new study supports body mass index as a useful tool for assessing obesity and health.

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A correlation between obesity and income has only developed in the past 30 years

It is well known that poorer Americans are more likely to be obese or suffer from diabetes; there is a strong negative correlation between household income and both obesity and diabetes. This negative correlation, however, has only developed in the past 30 years, according to researchers. Since 1990, the rise of obesity and diabetes was fastest among the poorest US regions.

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Study links frequent red meat consumption to high levels of chemical associated with heart disease

Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide (TMAO), that also is linked to heart disease. Scientists found that people who eat a diet rich in red meat have triple the TMAO levels of those who eat a diet rich in either white meat or mostly plant-based proteins, but discontinuation of red meat eventually lowers those TMAO levels.

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New evidence that females might benefit most from a low-salt diet

A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.

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All-Hands-on-Deck: NCCIH Needs You To Respond to the NIH HEAL Initiative

In this blog post, NCCIH director Dr. Helene Langevin and deputy director Dr. David Shurtleff discuss the HEAL (Helping to End Addiction Long-Term) Initiative and NCCIH’s participation in the project.

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Reducing variations in feeding practices and fortifying breast milk helps micro-preemies grow

Standardizing feeding practices, including the timing for fortifying breast milk and formula with essential elements like zinc and protein, improves growth trends for the tiniest preterm infants, according to new research.

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Obesity, risk of cognitive dysfunction? Consider high-intensity interval exercise

Researchers have discovered what might be an effective strategy to prevent and combat cognitive dysfunction in obese individuals. They are the first to examine the modulatory role of an exercise-induced protein in the brain that promotes neuron survival and used high-intensity interval exercise (HIIE) in obese and normal-weight subjects. Obesity reduces the expression of this protein and lower levels are associated with Alzheimer's, Parkinson's and obesity. HIIE upregulated this protein in the obese subjects compared to normal-weight subjects.

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Diabetes remission predictors in bariatric surgery

Researchers have improved a standard bariatric surgery clinical scoring system (DiaRem) to extend the prediction time for diabetic remission following bariatric (weight-loss) surgery.

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How vial sizes can be optimized to reduce pharmaceutical wastage

A new study shows how drug manufacturers can reduce wastage, and therefore their costs, by altering the size of the vials they produce.

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Obesity intervention needed before pregnancy

New research supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant.

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What's behind Mediterranean diet and lower cardiovascular risk?

A new study offers insights from a cohort study of women in the U.S. who reported consuming a Mediterranean-type diet.

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DDT in Alaska meltwater poses cancer risk for people who eat lots of fish

Children in Alaska whose diet includes a lot of fish from rivers fed by the Eastern Alaska Mountain Range may have a long-term elevated risk for cancer because of insecticides -- including DDT -- in the meltwater.

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Hazelnuts improve older adults' micronutrient levels, study shows

Older adults who added hazelnuts to their diet for a few months significantly improved their levels of two key micronutrients.

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Blood vessel growth key to healthy fat tissue, research shows

New research shows that inhibiting a protein within blood vessels stimulates new blood vessel growth, resulting in healthier fat tissue (adipose) and lower blood sugar levels. The findings provide key insight into how improving blood vessel growth could help to mitigate serious health problems that arise with obesity, such as diabetes.

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Gut microbiome differs among ethnicities

Changing the gut microbiome to beat illness really does hold great potential, said a biologist, but first scientists must answer what constitutes a healthy gut microbiome and in whom.

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Older women who suffer tooth loss more likely to develop high blood pressure

A study indicates that postmenopausal women who experience tooth loss are at higher risk of developing high blood pressure.

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The Importance of Epidemiology to NCCIH

In this blog post, Dr. Richard Nahin, lead epidemiologist at NCCIH, discusses the importance of studying trends in populations and how that relates to complementary and integrative practices, as well as the study of chronic pain.

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Gene that lets you eat as much as you want holds promise against obesity

It sounds too good to be true, but a novel approach that might allow you to eat as much as you want without gaining weight could be a reality in the near future. When a single gene known as RCAN1 was removed in mice and they were fed a high fat diet, they failed to gain weight, even after gorging on high fat foods for prolonged periods.

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High childhood BMI linked to obesity at age 24 in women

Girls who gain weight more rapidly between the ages of 5 and 15 are more likely to be obese at age 24, according to researchers.

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Alcohol intake may be key to long-term weight loss for people with Diabetes

A new study suggests that alcohol consumption may attenuate long-term weight loss in adults with Type 2 diabetes.

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Study takes stand on true health benefits of getting up out of your chair

A new health study provides fresh insights on the energy cost of sitting versus standing for sedentary workers.

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A Mediterranean diet in pregnancy is associated with lower risk of accelerated growth

Over 2,700 women and their children participated in this study that highlights the benefits of a healthy diet.

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One-Day Workshop To Focus on Cannabinoid Research

I want to share some details with you about an upcoming workshop on cannabinoid research. Sponsored by the National Center for Complementary and Integrative Health (NCCIH), “Evaluating the Therapeutic Potential of Cannabinoids: How To Conduct Research Within the Current Regulatory Framework” will take place on Saturday, December 8 from 8:00 a.m. to 5:15 p.m. ET.

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Is being a night owl bad for your health?

In the first ever international review of studies analysing whether being an early riser or a night owl can influence your health, researchers have uncovered a growing body of evidence indicating an increased risk of ill health in people with an evening preference as they have more erratic eating patterns and consume more unhealthy foods.

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Weight cycling is associated with a higher risk of death

Weight cycling is associated with a higher risk of death, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

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Extract from soursop leaves can prevent the symptoms of fibromyalgia, study suggests

The consumption of extract of Annona muricata L. leaves in pharmaceutical form and in the correct dosage can reduce the chronic pain, anxiety and depression that accompany this disease.

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Baby up at night? Inactivity may be a culprit

New research suggests babies who are less active get less sleep, something new parents may want to consider when looking for possible solutions for the long, sleepless nights.

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Views of ideal female appearance in China are changing

A researcher found that young women in China, living in a rapidly changing society with more personal independence, disposable income and exposure to Western media than ever before, are also altering their views of female beauty. Her research aims to determine whether these factors are leading to increasing body image concerns such as eating disorders and weight and shape concerns that have been reported in Asia.

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Only 12 percent of American adults are metabolically healthy, study finds

The prevalence of metabolic health in American adults is 'alarmingly low,' even among people who are normal weight, according to a new study. Only one in eight Americans is achieving optimal metabolic health. This carries serious implications for public health since poor metabolic health leaves people more vulnerable to developing Type 2 diabetes, cardiovascular disease and other serious health issues.

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Despite common obesity gene variants obese children lose weight after lifestyle changes

Children who are genetically predisposed to overweight, due to common gene variants, can still lose weight by changing their diet and exercise habits, according to a new study.

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When to Give Kids Medicine for Coughs and Colds

Sometimes a cold is just a cold. What can worried parents do when their babies and young children have a cold or cough? The FDA has some advice and tips.

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Bratman Describes Science of Nature’s Effects on Psychological Health

How contact with nature—whether outdoors or indoors (e.g., from plants or window views)—is an emerging field of research showing potential to help address some important public-health problems, said Gregory Bratman, Ph.D., in a recent lecture at NIH.

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Good help in primary care for children with obesity

Children treated for obesity in primary or outpatient care have a relatively good chance of fending off weight problems over the next few years as well, a study shows.

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Weight loss procedure shrinks both fat and muscle

Left gastric artery embolization, a novel interventional procedure used to treat obesity, leads to the loss of both fat and muscle, according to a new study. Researchers said the loss of muscle mass is concerning and underscores the importance of proper nutritional counseling after the procedure.

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Study in mice suggests drug to turn fat 'brown' could help fight obesity

Our bodies contain two types of fat: white fat and brown fat. While white fat stores calories, brown fat burns energy and could help us lose weight. Now, scientists have found a way of making the white fat 'browner' and increasing the efficiency of brown fat. While their study was carried out in mice, they hope that this finding will translate into humans and provide a potential new drug to help fight obesity.

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Intermittent fasting: No advantage over conventional weight loss diets

Intermittent fasting helps lose weight and promotes health. However, it is not superior to conventional calorie restriction diets, scientists have found out in the largest investigation on intermittent fasting to date. The scientists conclude that there are many paths leading to a healthier weight. Everybody must find a diet plan that fits them best and then just do it!

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Weight likely cause for one-fourth of asthma cases in kids with obesity

A study including health data for more than 500,000 children in the US suggests obesity might be to blame for about a quarter (23 to 27 percent) of asthma in children who are obese. This could mean about 10 percent of all kids ages 2 to 17 with asthma -- almost 1 million children in the US -- might have avoided the illness by maintaining a healthy weight.

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Routine vitamin B12 screening may prevent irreversible nerve damage in type-2 diabetes

Patients with type-2 diabetes, taking metformin, should have their vitamin B12 levels assessed more regularly to avoid irreversible nerve damage, according to a new study. The study findings suggest that earlier detection of vitamin B12 deficiency through routine screening of all metformin-treated, type-2 diabetes patients could reduce their risk of developing irreversible, painful and potentially disabling nerve damage.

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Antioxidants may prevent cognitive impairment in diabetes

Cognitive difficulties in patients with diabetes, caused by repeated episodes of low blood sugar, could be reduced with antioxidants, according to a new study. The study findings suggest that stimulating antioxidant defenses in mice reduces cognitive impairments caused by low blood sugar, which could help to improve the quality of life for diabetic patients.

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Parental 'feeding styles' reflect children's genes

New research challenges the idea that a child's weight largely reflects the way their parents feed them. Instead, parents appear to adopt feeding styles in response to their children's natural body weight, which is largely genetically influenced.

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Study of two tribes sheds light on role of Western-influenced diet in blood pressure

A South American tribe living in near-total isolation with no Western dietary influences showed no increase in average blood pressure from age one to age 60, according to a new study. In comparison, a nearby tribe whose diet includes some processed foods and salt did show higher blood pressure into late middle age.

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New Study Identifies a Neural Circuit Involved in the Response to Painful Heat

A newly identified pathway involving the spinal cord and two parts of the brainstem plays a key role in behavioral responses to an uncomfortable heat stimulus, according to a study in mice from the National Center for Complementary and Integrative Health’s Division of Intramural Research. The study was published in a recent issue of the journal Neuron.

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Study explains behavioral reaction to painful experiences

This press release describes basic research related to understanding the nature of pain.

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Dietary fat is good? Dietary fat is bad? Coming to consensus

Which is better, a low-fat/high-carbohydrate diet or a high-fat/low-carbohydrate diet -- or is it the type of fat that matters? In a new paper, researchers with diverse expertise and perspectives on the issues laid out the case for each position and came to a consensus and a future research agenda.

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Low-carb diets cause people to burn more calories

Most people regain the weight they lose from dieting within one or two years, in part because the body adapts by slowing metabolism and burning fewer calories. A meticulous study now finds that eating fewer carbohydrates increases the number of calories burned. The findings suggest that low-carb diets can help people maintain weight loss, making obesity treatment more effective.

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Checking very preterm babies' head size can help identify long-term IQ problems

Regular early head circumference assessments add valuable information when screening for long-term neurocognitive risk - according to new research.

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Should you eat a low-gluten diet?

When healthy people eat a low-gluten and fiber-rich diet compared with a high-gluten diet they experience less intestinal discomfort including less bloating which researchers show are due to changes of the composition and function of gut bacteria. The new study also shows a modest weight loss following low-gluten dieting. The researchers attribute the impact of diet on healthy adults more to change in composition of dietary fibers than gluten itself.

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Use of Yoga, Meditation, and Chiropractic by Adults and Children

This issue of NCCIH’s Clinical Digest discusses the most recent findings from the National Health Interview Survey on the use of yoga, meditation, and chiropractic.

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Media Advisory: Lecture to explore health care transformation through the VA’s patient-centered model

What: Tracy W. Gaudet, M.D., inaugural executive director, Office of Patient Centered Care and Cultural Transformation, Veterans Health Administration, U.S. Department of Veterans Affairs, will present on “Transforming Veterans’ Health: Implementing a Whole Health System of Care.”

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Weightlifting is good for your heart and it doesn't take much

Lifting weights for less than an hour a week may reduce your risk for a heart attack or stroke by 40 to 70 percent, according to a new study. Spending more than an hour in the weight room did not yield any additional benefit, the researchers found. The results show benefits of strength training are independent of running, walking or other aerobic activity.

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If your diet fails, try again; your heart will thank you

Risk factors for cardiovascular disease closely track with changes in eating patterns, even only after a month or so.

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Treating obesity: One size does not fit all

Understanding the very different characteristics of subgroups of obese patients may hold the key to devising more effective treatments and interventions, new research found.

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'Strongest evidence yet' that being obese causes depression

New research has found the strongest evidence yet that obesity causes depression, even in the absence of other health problems.

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Weight during adolescence may affect pancreatic cancer risk in adulthood

New research has linked adolescent obesity with up to a four-fold increased risk of pancreatic cancer later in life. The study's results also suggest that overweight and even higher weight within the 'normal' weight range in men may increase pancreatic cancer risk in a graded manner.

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Big change from small player: Mitochondria alter body metabolism and gene expression

Mitochondria have their own DNA, but the 13 genes in human mitochondria -- along with DNA sequences for tRNAs, rRNAs and some small peptides -- are massively overshadowed by the 20,000 genes in the human nucleus. Nevertheless, these diminutive mitochondria may have a strong influence on cellular metabolism and susceptibility to metabolic diseases like heart failure or obesity.

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How many calories do you burn? It depends on time of day

Researchers have made the surprising discovery that the number of calories people burn while at rest changes with the time of day. When at rest, people burn 10 percent more calories in the late afternoon and early evening than in the early morning hours.

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Nasal delivery of weight-loss hormone eases breathing problems in sleeping mice

Experimenting with mice, Johns Hopkins Medicine researchers have added to evidence that a hormone best known for helping regulate hunger and body weight might also ease breathing problems experienced during sleep more effectively when given through the nose.

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Manage Your Asthma: Know Your Triggers and Treatment Options

You can manage your asthma by taking medications approved by the FDA. Before going to the pharmacy, get a proper diagnosis from a doctor and together develop an asthma action plan.

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National Survey Reveals Increased Use of Yoga, Meditation, and Chiropractic Care Among U.S. Adults

New National Health Interview Survey (NHIS) data show rising use of yoga, meditation, chiropractic by U.S. adults.

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More adults and children are using yoga and meditation

[em]Nationwide survey reveals significant increases in use of mind and body approaches[/em]

Information in this press release on yoga, meditation, and chiropractic relates to new data from the 2017 National Health Interview Survey.

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National Survey Reveals Increased Use of Yoga and Meditation Among U.S. Children

New NHIS data show higher use rates of meditation, yoga by U.S. children.

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Some factors have a greater impact on heart attack risk in women than they do in men

High blood pressure, smoking and diabetes increase the risk of heart attack in both sexes but they have more impact in women than they do in men.

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Does a woman's weight gain during pregnancy affect children's bone health?

A new study has examined whether managing weight during pregnancy might affect children's bone mass. In under/normal weight mothers, weight gain during pregnancy was associated with slightly increased bone mass at seven years of age in children, while in overweight/obese mothers, no beneficial effect of weight gain on bone mass was observed.

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Eat your vegetables (and fish): Another reason why they may promote heart health

Elevated levels of trimethylamine N-oxide (TMAO) -- a compound linked with the consumption of fish, seafood and a primarily vegetarian diet -- may reduce hypertension-related heart disease symptoms. New research in rats finds that low-dose treatment with TMAO reduced heart thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension.

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Does having muscle weakness and obesity lead to falls for older women?

New research suggests that it is important to identify people at risk for falls related to obesity and muscle weakness so that healthcare providers can offer appropriate solutions.

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Gene that regulates fat accumulation and obesity

A new study showed that regardless of diet, a protein called Pannexin 1 significantly regulates the accumulation of fat in mice. The study suggests that a deletion of the Panx1 gene in the early stages of development of mouse fat cells increases the amount of fat accumulated, leading to a higher risk for obesity later in life.

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A hypocaloric Mediterranean diet and daily exercise maintain weight loss

Following a Mediterranean diet low in calories and engaging daily physical activity have been demonstrated to result in reduce body weight and cardiovascular risk in overweight patients and patients with metabolic syndrome, and to maintain these benefits after one year.

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Nuts for nuts? Daily serving may help control weight and benefit health

Eating Brazil nuts and other varieties of nuts daily may prevent weight gain and provide other cardiovascular benefits, according to two separate preliminary studies.

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Daily weighing may be key to losing weight

Daily weighing may help with weight loss goals. People who don't weigh themselves at all or rarely were less likely to lose weight than those who weighed themselves often, according to new research.

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Does dietary restriction protect against age-related leaky gut?

Flies on dietary restriction are protected from leaky gut and systemic inflammation as they age. Conversely, flies on a rich diet are more prone to intestinal permeability, developing gaps in the intestinal barrier which are caused by an age-related increase in the death of intestinal epithelial cells. Researchers also looked at dysbiosis as a contributor to leaky gut and concluded that diet may ultimately be the primary driver in cellular changes leading to intestinal permeability.

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Trial finds diet rich in fish helps fight asthma

A clinical trial has shown eating fish such as salmon, trout and sardines as part of a healthy diet can reduce asthma symptoms in children.

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Genetic factors tied to obesity may protect against diabetes

Some genetic variations associated with obesity actually protect against Type 2 diabetes, heart attack and stroke, new findings suggest.

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For older adults, does eating enough protein help delay disability?

A research team focused their attention on learning whether eating more protein could contribute to helping people maintain independence.

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How diet impact health and well-being

From the standpoint of heart health, the Tsimane are a model group. A population indigenous to the Bolivian Amazon, the Tsimane demonstrate next to no heart disease. They have minimal hypertension, low prevalence of obesity and and their cholesterol levels are relatively healthy. And those factors don't seem to change with age.

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Small association between early antibiotic exposure and weight gain in young children

A pioneering study conducted within a nationwide network finds that antibiotic use at <24 months of age was associated with slightly higher body weight at 5 years of age.

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Plant-based or vegan diet may be best for keeping type 2 diabetes in check

A predominantly plant-based or vegan diet may be best for keeping type 2 diabetes in check, not least because of its potential impact on mood, suggests a systematic review of the available evidence.

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To ward off fatty liver, breast is best for mom

Researchers have discovered that mothers who breastfed a child or children for six months or more are at lower risk for developing non-alcoholic fatty liver disease (NAFLD) years later during mid-life. With no other current prevention options aside from a healthy lifestyle, they say the finding may represent an early modifiable risk factor for a serious and chronic disease.

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Economic impact of excess weight now exceeds $1.7 trillion

The impact of obesity and overweight on the U.S. economy has eclipsed $1.7 trillion, an amount equivalent to 9.3 percent of the nation's gross domestic product, according to a new report on the role excess weight plays in the prevalence and cost of chronic diseases.

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Immigration to the United States changes a person's microbiome

Researchers new evidence that the gut microbiota of immigrants and refugees rapidly Westernize after a person's arrival in the United States. The study of communities migrating from Southeast Asia to the US could provide insight into some of the metabolic health issues, including obesity and diabetes, affecting immigrants to the country.

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Cottonseed oil linked to lower cholesterol

Researchers at the University of Georgia have found that a high-fat diet enriched with cottonseed oil drastically improved cholesterol profiles in young adult men.

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Inflammation can lead to circadian sleep disorders

Inflammation, which is the root cause of autoimmune disorders including arthritis, type 1 diabetes, irritable bowel syndrome and Crohn's disease, has unexpected effects on body clock function and can lead to sleep and shiftwork-type disorders, a new study in mice found.

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Xylitol and Your Dog: Danger, Paws Off

This sugar substitute, found in some human foods and dental products, can be poisonous to your dog.

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Could bariatric surgery make men more virile?

Men who have undergone bariatric surgery as a long-term way of losing weight might also benefit from increased testosterone levels post-surgery. However, there is no evidence that the sperm quality of a patient improves.

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Now's a Good Time to Get Your Flu Vaccine

Early in the fall is the best time to get your annual flu vaccine. Find out why it's important to get one.

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Vitamin D levels in the blood linked to cardiorespiratory fitness

New research finds that higher levels of vitamin D are associated with better exercise capacity.

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Fruit fly study challenges theories on evolution and high-carb diets

Fruit fly research challenges neutral theory of molecular evolution and suggests one day we may be prescribed diets according to our genes.

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Gut microbiota products can favor diabetes

A study shows that the gut microbiota has the ability to affect how cells respond to insulin, and can thus contribute to type 2 diabetes. The findings demonstrate an hereto unknown pathological mechanism.

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Tooth loss can indicate malnutrition, study finds

Older adults are at risk for both impaired oral health and malnutrition, according to a new study.

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Study of 500,000 people clarifies the risks of obesity

Elevated body mass index (BMI) -- a measure of weight accounting for a person's height -- has been shown to be a likely causal contributor to population patterns in mortality, according to a new study using measurements and mortality data from 500,000 people.

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Dr. Tracy Gaudet To Speak on Health Care Transformation in the VA’s Patient-Centered Model

In the 2018 Stephen E. Straus Distinguished Lecture, Dr. Tracy Gaudet will address the VA’s new Whole Health System, a new initiative to deliver personalized, proactive, and patient-centered care to U.S. veterans.

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Irish Famine victims' heavy smoking led to dental decay, new research reveals

Irish Famine victims were heavy smokers which caused badly rotten teeth, researchers have discovered.

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Researchers make mice lose weight by imitating effects from cold and nicotine

Inspired by some of the effects from winter swimming and smoking, researchers have found a way to improve the metabolism of mice and make them lose weight. They have done so by stimulating the body's so-called cold and nicotinic receptors.

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Differences between male and female fat tissue, and health

In a new study, researchers found that the abdominal fat on female mice had more blood vessels than the fat on male mice, and that this protected the health of the female mice as they gained fat from eating a high-fat diet.

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Poor oral health linked to higher blood pressure, worse blood pressure control

Poor oral health may interfere with blood pressure control in people diagnosed with hypertension. Periodontal disease -- a condition marked by gum infection, gum inflammation and tooth damage -- appears to worsen blood pressure and interferes with hypertension treatment. Study findings underscore the importance of good oral health in blood pressure control and its role in preventing the adverse cardiovascular effects known to stem from untreated hypertension.

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Complex causes of premature and low-birthweight babies in India

Women in India who spend more time fetching water, use a shared latrine, and endure harassment from others are more apt to give birth to a pre-term or low-birthweight baby.

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For a lower climate footprint, vegetarian diet beats local

A new study provides a more comprehensive accounting of the greenhouse gas emissions from EU diets. It shows that meat and dairy products are responsible for the lion's share of greenhouse emissions from the EU diet.

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Gut microbiota of infants predicts obesity in children

Evaluating the gut microbiota of infants may help identify children who are at risk for becoming overweight or obese. The research revealed that gut microbiota composition at two years of life is associated with body mass index (BMI) at age 12. In addition, the BMI at age two was not significantly higher in children who later became overweight/obese, indicating that gut microbiota composition may be the earliest warning sign for detecting obesity.

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When fathers exercise, children are healthier, even as adults

Most parents know that the diet and exercise habits of a pregnant woman impacts the health of her baby, but little is known about how a father's health choices are passed to his children. A new study finds that lifestyle practices of fathers prior to conception may have a major impact on the lifelong health of their children.

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Adding refined fiber to processed food could have negative health effects, study finds

Adding highly refined fiber to processed foods could have negative effects on human health, such as promoting liver cancer, according to a new study.

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Weight loss success linked with active self-control regions of the brain

New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control.

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Did eating starchy foods give humans an evolutionary advantage?

Gene AMY1, which kickstarts digestion of starch in the mouth, is associated with blood glucose levels and digestion of carbohydrates, with implications for understanding human evolutionary biology and the gut microbiome.

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Children with autism, developmental delays nearly 50 percent more likely to be overweight, obese

A new study reveals that children with developmental delays, including autism spectrum disorder (ASD), are up to 50 percent more likely to be overweight or obese compared with the general population.

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Carbon fiber can store energy in the body of a vehicle

A study has shown that carbon fibers can work as battery electrodes, storing energy directly. This opens up new opportunities for structural batteries, where the carbon fiber becomes part of the energy system. The use of this type of multifunctional material can contribute to a significant weight-reduction in the aircraft and vehicles of the future -- a key challenge for electrification.

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New Report Reflects NCCIH Research Interest in Emotional Well-being

In this blog post, Dr. Emmeline Edwards discusses an NIH/NCCIH research initiative to advance the study of emotional well-being.

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Fat Burners Zone Issues Voluntary Nationwide Recall of Zero Xtreme Due to Presence of Undeclared Sibutramine

Fat Burners Zone is voluntarily recalling 1 lot of Zero Xtreme capsules due to contamination with sibutramine, which may increase the risk for patients with a history of coronary artery disease, congestive heart failure, arrhythmias, or stroke.

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Nutrition has a greater impact on bone strength than exercise

One question that scientists and fitness experts alike would love to answer is whether exercise or nutrition has a bigger positive impact on bone strength.

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Diets rich in fish oil could slow the spread and growth of breast cancer cells

Omega-3 fatty acids, such as those typically contained in fish oil, may suppress the growth and spread of breast cancer cells in mice.

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Last Call: Opportunity to Provide Input to NIH for Back Pain Consortium Research Program by October 18, 2018

Given our Center’s longstanding interests in funding rigorous research of complementary and integrative health approaches for pain, we are enthusiastic about a potential new translational research initiative that will address the need for effective and personalized therapies for chronic low back pain – the NIH Back Pain Research Consortium (BACPAC). 

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Parasites from medieval latrines unlock secrets of human history

A radical new approach combining archaeology, genetics and microscopy can reveal long-forgotten secrets of human diet, sanitation and movement from studying parasites in ancient excrement, according to new research.

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Endurance exercise training has beneficial effects on gut microbiota composition

According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.

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Fat: A new player expands our definition of diabetes

Type 2 diabetes is reaching epidemic proportions around the world. The World Health Organization reports that more than 422 million people suffer from the disease, including over 1.2 million in Australia alone. The consequences of diabetes can be dire (cancer, kidney failure, and heart attacks) and its prevalence is rising fast. There is an urgent need to better understand how diabetes progresses -- and how it might be stopped.

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Ketogenic diet appears to prevent cognitive decline in mice, study finds

The Ketogenic Diet, simple caloric restriction, or the pharmaceutical rapamycin appear to improve neurovascular function and prevent cognitive decline in animal models.

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Babies of overweight mothers may risk developing self-regulation problems

A mother's weight during early pregnancy may affect how well her baby is able to self-regulate during its first months and years of life. This is according to a study of more than 3100 Finnish women.

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Effects of a high-fat diet may be passed on for three generations

A high-fat diet in female mice affects their offspring's obesity, insulin resistance and addictive-like behaviors for three generations, according to a new study.

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The metabolome: A way to measure obesity and health beyond BMI

The current standard for determining obesity is body mass index (BMI), a simple mathematical formula that uses weight and height. A new study looks at both the metabolome and the genome, and their relationship to BMI.

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Low copper levels linked to fatter fat cells

In studies of mouse cells, researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

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Sprayology Issues Voluntary Nationwide Recall of Homeopathic Aqueous-Based Medicines Due to Microbial Contamination

Eight and Company LLC, d/b/a Sprayology recalls all lots within expiry from 10/18-7/22 of its aqueous-based homeopathic product line for human use (manufactured by King Bio) due to possible microbial contamination.

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Study identifies gene that makes gentle touch feel painful after injury

New research suggests the PIEZO2 gene may play an essential role in the nervous system’s reaction to injury and inflammation, making it a target for developing precise treatments for relieving pain caused by cuts, burns, and other skin injuries.

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PIEZO2 Ion Channel Presents New Target for Pain Research

New NCCIH-supported research suggests the PIEZO2 mechanoreceptor is essential for light touch detection after injury in mice and humans, and that PIEZO2 antagonists may provide a new avenue for relieving a variety of chronic pain conditions.

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Ideal protein to help seniors rebuild lost muscle

While exercise buffs have long used protein supplements to gain muscle, new research suggests one protein source in particular, whey protein, is most effective for seniors struggling to rebuild muscle lost from inactivity associated with illness or long hospital stays.

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Gene mutation points to new way to fight diabetes, obesity, heart disease

Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a distinct advantage over those who do not. Those with the mutation have a lower risk of diabetes, obesity, heart failure, and even death.

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NIH research projects to track activities of gut-derived metabolites

This press release describes NCCIH research awards to scientists studying possible links between gut microflora and the transformation of dietary compounds into substances known as metabolites.

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Study firms up diet and depression link

In an unusual experiment, researchers have found that among Torres Strait Islander people the amount of fish and processed food eaten is related to depression.

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Community efforts to combat childhood obesity can be effective, study finds

New research examines how broadly and successfully communities across the US implement programs and policies to prevent obesity in kids.

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Too much vitamin A may increase risk of bone fractures

Consuming too much vitamin A may decrease bone thickness, leading to weak and fracture prone bones, according to a new study in mice.

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Planned intermittent fasting may help reverse type 2 diabetes, suggest doctors

Planned intermittent fasting may help to reverse type 2 diabetes, suggest doctors after three patients in their care, who did this, were able to cut out the need for insulin treatment altogether.

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NIH research projects to track activities of gut-derived metabolites

This press release describes NCCIH research awards to scientists studying possible links between gut microflora and the transformation of dietary compounds into substances known as metabolites.

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Diet and weight may affect response to bipolar disorder treatment

Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to contribute to general inflammation. These are early results, but if replicated may mean that treatment of some mental health problems could benefit from the inclusion of dietary advice.

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Gastric banding as effective as metformin in slowing prediabetes, type two diabetes

People with prediabetes or new-onset type 2 diabetes who had gastric banding, a type of bariatric surgery for weight loss, had similar stabilization of their disease to those who took metformin alone, according to a new study.

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Weight loss drug shows positive effect on diabetes

A new study has found that lorcaserin decreased risk for diabetes, induced diabetes remission and reduced risk of diabetes complications in obese and overweight patients.

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Diet rich in fried and processed foods linked to increased hypertension in black Americans

New findings suggest that diet is a major contributor for the increased risk of hypertension in black compared to white Americans.

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Tarragon supplements may make healthy women gain weight

Russian tarragon and bitter melon supplements may be less helpful for women than men when it comes to combating metabolic syndrome, whose symptoms include high blood sugar, high blood pressure and excess fat around the waist, a new study suggests.

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Chemotherapy may lead to mitochondrial dysfunction in skeletal muscle

Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction, according to new research. Dysfunctional mitochondria, the energy centers of the cells, may contribute to fatigue and weakness that some people with breast cancer experience through the course of disease treatment.

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New Study Links Mindfulness, Brain Changes, and Pain Sensitivity

People who are naturally more mindful report less pain and show lower activation of a specific region of the brain in response to an unpleasant heat stimulus, according to a new study supported by the National Center for Complementary and Integrative Health (NCCIH). The study, conducted by researchers from Wake Forest University and collaborating institutions, was published in the journal Pain.

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How has the gluten-free industry affected individuals with celiac disease?

A new study looks at how the recent proliferation of the gluten-free industry has affected individuals living with celiac disease.

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Newly discovered compounds shed fresh light on whole grain health benefits

Scientists have discovered new compounds that may explain whole grain health benefits. A high intake of whole grains increased the levels of betaine compounds in the body which, in turn, was associated with improved glucose metabolism, among other things. The findings shed new light on the cell level effects of a whole grain-rich diet, and can help in development of increasingly healthy food products.

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One more year of high school may shape waistlines later in life

Together, genetics and years of education can influence whether or not someone becomes obese, a new study finds.

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A web-based program is as effective as group counseling for patients with non-alcoholic fatty liver disease

Lifestyle changes are the cornerstone of preventing and treating non-alcoholic fatty liver disease (NAFLD). Scientists report success in using web-based intervention to manage lifestyle changes in patients with NAFLD in a new six-year single-center study comparing group-based and web-based interventions.

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Diet affects the breast microbiome in mammals

Diet influences the composition of microbial populations in the mammary glands of nonhuman primates, researchers report. Specifically, a Mediterranean diet increased the abundance of probiotic bacteria previously shown to inhibit tumor growth in animals.

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Drug cocktail may treat postmenopausal PCOS complications

A combination of a diabetes drug and a high blood pressure medication may effectively treat all symptoms of postmenopausal polycystic ovary syndrome (PCOS).

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Mediterranean diet prevents a leading cause of blindness, study suggests

Evidence is mounting that a poor diet plays an important role in the development of age-related macular degeneration (AMD), a leading cause of blindness in the United States.

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Yo-yoing weight, blood pressure, cholesterol and blood sugar readings may raise heart attack and stroke risk

People with fluctuating weight, blood pressure, cholesterol and/or blood sugar levels are at higher risk of heart attack and stroke than those with more stable readings. Having more measures that fluctuate adds to the risk.

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Cancer hijacks the microbiome to glut itself on glucose

A new study shows that leukemia actively undercuts the ability of normal cells to consume glucose, thus leaving more glucose available to feed its own growth.

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Vitamin D supplements may promote weight loss in obese children

Vitamin D supplements may promote weight loss and reduce risk factors for future heart and metabolic disease in overweight and obese children, according to new research. These findings indicate that simple vitamin D supplementation may be part of an effective strategy to tackle childhood obesity and reduce the risk of serious health problems, such as heart disease, in adulthood.

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The hormone FGF23 is linked to structural deficits in the brain

Scientists find that high levels of a hormone called FGF23 are linked to changes in brain structure. They are associated with structural changes in the brain's frontal lobes.

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Improved In vivo imaging of atherosclerotic plaque development

Researchers have developed a method for quantitatively assessing atherosclerotic plaque buildup in mice. They transplanted X-ray-irradiated low-density-lipoprotein-knockout mice with bone marrow cells expressing near-infrared fluorescent protein, which subsequently developed into fluorescent macrophages. These macrophages congregated specifically in atherosclerotic plaques that arose after feeding on a high-cholesterol diet. In vivo imaging detected the amount of aortic plaque formed and its change over time, which could help in assessing the efficacy of anti-atherosclerotic drugs.

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Bariatric surgery linked to safer childbirth for the mother

Obese mothers who lose weight through bariatric surgery can have safer deliveries, according to an observational study. Positive effects include fewer caesarean sections, infections, tears and hemorrhages, and fewer cases of post-term delivery or uterine inertia.

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The quality of protein supplements for athletes

Powdered protein supplements are one of the most commonly consumed nutritional supplements, whether by professional athletes or amateurs.

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Lifestyle intervention may mitigate weight gain due to ubiquitous contaminant

A new study finds that perfluoroalkyl and polyfluoroalkyl substances (PFASs) are associated with increases in weight, but exercise and diet may reduce the obesogenic effects of these environmental contaminants.

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Screening using body mass index alone may miss every second preschooler with excess stomach fat

When assessing whether preschoolers are overweight, health professionals should use other measures such as waist-to-height ratio in addition to the body mass index (BMI). A study shows that this is because measuring the BMI of younger children often fails to identify those with excess stomach fat and possible associated health problems.

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Interaction with Evidence-based Guidelines a Featured Topic in October 5th Advisory Council Meeting

In this blog post, Dr. Partap Khalsa highlights key presentations and concepts to be discussed at the October 5, 2019 meeting of the National Advisory Council for Complementary and Integrative Health.

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Physical activity necessary to maintain heart-healthy lifestyle

Exercise and physical activity are of vast global importance to prevent and control the increasing problem of heart disease and stroke, according to a review article.

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Overweight pregnant women can safely cut calories, restrict weight gain

With proper nutrition guidance, it is safe and feasible to restrict weight gain in obese and overweight pregnant women, a new study shows.

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Weight loss can be boosted fivefold thanks to novel mental imagery technique

A new study has shown how overweight people lost an average of five times more weight using Functional Imagery Training (FIT) -- a brief individual motivational intervention that teaches self-motivating skills using mental imagery -- compared with talking therapy alone.

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Researchers explore how changes in diet alter microbiome in artificial intestine

Using an artificial intestine they created, researchers have shown that the microbiome can quickly adapt from the bacterial equivalent of a typical western diet to one composed exclusively of dietary fats.

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Insulin shows great potential against chronic colitis

Diabetes is not the only disease on which insulin has an effect, it appears. In a new study that involved tests on mice researchers have discovered a new method for treating chronic colitis with regular insulin. The researchers have set up a company with a view to testing the treatment and hopefully making it available to patients.

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Kiwi teenagers less fit than a generation ago

New Zealand teenagers are less fit and weigh more than their parents were at the same age, new University of Otago research reveals.

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Mediterranean-style diet may lower women's stroke risk

Following a Mediterranean-style diet (high in fish, fruits and nuts, vegetables and beans and lower in meat and dairy) reduced stroke risk in women over 40, but not in men. The Mediterranean-style diet reduced stroke risk among white adults who were at high risk of cardiovascular disease.

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High gluten diet in pregnancy linked to increased risk of diabetes in children

A new study suggests that a high gluten intake by mothers during pregnancy is associated with an increased risk of their child developing type 1 diabetes.

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New Grants To Study Behavioral Interventions for Opioid Addiction and Recovery

Overdose deaths, opioid misuse, addiction to prescription opioids or to illicit drugs such as heroin, and chronic pain management are tough problems that are often related to each other. Together, they form a daunting public health crisis that is of great concern and significance to many in the United States, including the National Center for Complementary and Integrative Health (NCCIH) and much of the National Institutes of Health (NIH). 

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Fish-rich diets in pregnancy may boost babies' brain development

Women could enhance the development of their unborn child's eyesight and brain function by regularly eating fatty fish during pregnancy. This is the suggestion from a small-scale study. The research supports previous findings that show how important a prospective mother's diet and lifestyle choices are for the development of her baby.

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Intestines modify their cellular structure in response to diet

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility.

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Anti-inflammatory protein promotes healthy gut bacteria to curb obesity

Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported that the NLRP12 gene is underactive in people who are obese, making it a potential therapeutic target for treating obesity and diabetes, both of which are risk factors for cardiovascular disease and other serious conditions.

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NIH announces awards for behavioral research on OUD prevention and treatment

This press release provides information about NCCIH research awards to study the impact of behavioral interventions for primary or secondary prevention of opioid use disorder (OUD) or as complements to medication-assisted treatment (MAT).

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Young children's oral bacteria may predict obesity

Weight gain during early childhood is related to the composition of oral bacteria of two-year-old children, suggesting this understudied aspect of a children's collection of microorganisms could serve as an early indicator for childhood obesity.

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Green tea compound helps siRNA slip inside cells

Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant in green tea called epigallocatechin gallate (EGCG) appears to have beneficial effects in cells and animals. Now, researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells.

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Strength-based exercises could help child obesity fight, study finds

Encouraging young people to do strength-based exercises -- such as squats, push ups and lunges -- could play a key role in tackling child obesity, research suggests.

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Sugar content of most supermarket yogurts well above recommended threshold

The sugar content of most types of yogurt is well above the recommended threshold, reveals an analysis of the nutrient content of available UK supermarket products. And organic varieties, often viewed as healthier options, contain some of the highest average sugar content, at 13.1 g/100 g, the findings indicate.

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Father's obesity in early puberty doubles asthma-risk for future offspring

Boys who have considerable weight gain between childhood and puberty, double the risk of having asthma as an adult, and for future offspring.

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New Research Career Development Funding Opportunity for Complementary and Integrative Health Clinician-Scientists

In this research blog, Dr. Lanay Mudd discusses career development pathways for clinician-scientists and a new career development funding opportunity in partnership with the National Center for Advancing Translational Sciences (NCATS).

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Either too much or too little weight gain during pregnancy is associated with adverse outcomes in children aged 7 years

New research shows that if a woman gains either too much or too little weight during pregnancy, there are adverse effects in children at 7 years of age.

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Stress over fussy eating prompts parents to pressure or reward at mealtime

Mothers report higher level of concern about long-term health consequences for fussy eaters, according to a new study.

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Beaumont Bio Med, Inc. Issues Voluntary Nationwide Recall of all their Homeopathic Aqueous/Alcohol-Based Medicines due to the Nationwide Recall by the Contract Manufacturer, King Bio, of all their Aqueous-Based Products-Possible Microbial Contamination

Beaumont Bio Med, Inc. is voluntarily recalling its entire aqueous/alcohol-based product line for human use due to possible microbial contamination.

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Hellolife, Inc. Issues Voluntary Worldwide Recall of Neuroveen, Respitrol, Thyroveev and Compulsin due to Possible Microbial Contamination

HelloLife, Inc. voluntarily recalls products due to possible microbial contamination.

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BioLyte Laboratories Issues Voluntary Nationwide Recall Due to the Voluntary Nationwide Recall initiated by King Bio Inc. (a Raw Material Supplier) for NeoRelief for Muscle Cramping and Restlessness Topical Gel Due to Possible Microbial Contamination

BioLyte Laboratories recalls lot numbers 1138, 1139, 1146, and 1160 of NeoRelief for Muscle Cramping and Restlessness Topical Gel.

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Household cleaning products may contribute to kids' overweight by altering their gut microbiota

Commonly used household cleaners could be making children overweight by altering their gut microbiota, suggests a new study.

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Diagnosing and treating resistant hypertension

A new statement from the American Heart Association provides a comprehensive overview of how to diagnose and treat hypertension based on a review of available scientific information.

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Calorie counts on restaurant menus have customers ordering less

Researchers conducted a randomized experiment and found that diners at full service restaurants whose menus listed calories ordered meals with 3 percent fewer calories -- about 45 calories less -- than those who had menus without calorie information. Customers ordered fewer calories in their appetizer and entree courses, but their dessert and drink orders remained the same.

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Anti-inflammatory diet linked to reduced risk of early death

A new study finds that adhering to an anti-inflammatory diet is associated with lower risks of dying from any cause, dying from cardiovascular causes, and dying from cancer.

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Dietary fiber reduces brain inflammation during aging

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function. That's one explanation for why memory fades and other brain functions decline during old age. But, according to a new study, there may be a remedy to delay the inevitable: dietary fiber.

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Defining the Prevalence of Chronic Pain in the United States

This Research Spotlight highlights new data suggesting that in 2016 nearly 20 percent of U.S. adults had chronic pain and 8 percent had high-impact chronic pain (pain that limited at least one major life activity).

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Yoga for Pain

This issue of NCCIH Clinical Digest offers information on yoga and certain pain conditions.

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New tool screens online health ads for deception

Experts have devised a simple screening tool to evaluate if the products popping up on your newsfeed are likely to be scams.

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Intense, recent physical activity linked to healthy metabolic profiles in adolescents

More time spent intensely active, to a greater extent than less time spent sedentary, correlates with a healthier metabolic profile in adolescence, according to a new study.

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Among body shapes, pears are healthier than apples

For women, fat usually accumulates around the hips, resulting in a pear-shaped look. In men, fat tends to build up around the abdomen, creating an apple shape. According to a new mouse study, it's healthier to be a pear than an apple.

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High blood sugar during pregnancy ups risk of mother's type 2 diabetes, child's obesity

Mothers with elevated blood glucose during pregnancy -- even if not high enough to meet the traditional definition of gestational diabetes -- were significantly more likely to have developed type 2 diabetes a decade after pregnancy than their counterparts without high blood glucose.

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Sarcolipin tricks muscle cells into using more energy, burning fat

Ever wonder why you burn fat and heat up when you exercise or shiver? Now, researchers have shown that sarcolipin, a small peptide only found in muscles, increases muscle energy expenditure and fat oxidization.

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Immune cells destroy healthy brain connections, diminish cognitive function in obese mice

Obesity leads to cognitive impairment by activating microglial cells, which consume otherwise functional synapses in the hippocampus, according to a study of male mice. The research suggests that microglia may be a potential therapeutic target for one of the lesser known effects of this global health epidemic on the brain.

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Change your diet to save both water and your health

Shifting to a healthy diet is not only good for us, but it also saves a lot of fresh water, according to a new study. Compared to existing diets, the water required to produce our food could be reduced by up to 55 percent for healthy pescetarian and vegetarian diets.

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"My Medicines" ... This Brochure Can be a Lifesaver

"My Medicines" a brochure offered by FDA's Office of Women's Health, can play a vital role in the medical treatment you receive during an emergency.

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Scientists block RNA silencing protein in liver to prevent obesity and diabetes in mice

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat-related and diabetic conditions.

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Lifestyle changes reduce the need for blood pressure medications

Men and women with high blood pressure reduced the need for antihypertensive medications by making lifestyle changes. A 16-week program, focused on the DASH diet, weight management and exercise, resulted in the most dramatic declines in blood pressure.

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Lifestyle Interventions May Limit Weight Gain During Pregnancy in Overweight or Obese Women

In a new study, behavioral lifestyle intervention programs that focused primarily on diet and physical activity limited weight gain during pregnancy in overweight or obese women.

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Pregnant women can safely control weight gain through diet and lifestyle changes

Many overweight/obese women gain too much weight during pregnancy. New trials showed these women can safely limit their weight gain with diet and exercise interventions. The reduced weight gain, however, did not result in fewer obstetrical complications. The finding suggests that the lifestyle changes need to start before pregnancy.

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Rapid weight gain during infancy possible risk factor for later obesity in kids with autism

A recent study found that children with Autism Spectrum Disorder (ASD) had the highest frequency of rapid weight gain during the first six months of life, which may put them at increased risk for childhood obesity.

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Public health researchers warn of dietary supplements containing higenamine

A new peer-reviewed study of weight-loss and sports/energy supplements containing higenamine finds unpredictable and inaccurately labeled dosages of the potentially harmful cardiovascular stimulant.

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A Note on NCCIH Activities Related to Music, Health, and Child Development

In this research blog, Dr. Emmeline Edwards discusses an upcoming FOA that promotes research on music and health.

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Communication among organs, tissues regulating body's energy revealed

Researchers have identified a system of communication networks that exists among organs and tissues that regulate metabolism. Findings from their study provide, for the first time, a detailed 'atlas' illustrating how the body creates and uses energy, and how imbalances in the networks may impact overall health.

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Longer daily fasting times improve health and longevity in mice

Increasing time between meals made male mice healthier overall and live longer compared to mice who ate more frequently, according to a new study.

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What Anglo Saxon teeth can tell us about modern health

Evidence from the teeth of Anglo Saxon children could help identify modern children most at risk from conditions such as obesity, diabetes and heart disease.

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NIH study broadens understanding of High Impact Chronic Pain in the US

Researchers have demonstrated that disability is as likely in the chronic pain population as it is in those with kidney failure, emphysema or stroke. This is the reality for 11 million U.S. adults with High Impact Chronic Pain (HICP), a new concept that describes those with pain lasting three months or longer and accompanied by at least one major activity restriction.

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Whole grains one of the most important food groups for preventing type 2 diabetes

It doesn't matter if it's rye, oats, or wheat. As long as it is whole grain, it can prevent type 2 diabetes, according to the results of a new study.

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Fish oil supplement in pregnancy is linked to increase in lean and bone mass by age 6 years

Taking fish oil supplements in the later stages of pregnancy is associated with a higher weight (BMI) in children in the first six years of life, but not an increased risk of overweight or obesity by age 6, a new study suggests.

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Ways to maximize nutrition and growth for the smallest preemies

To help clinicians maximize nutrition and growth in very low birth weight infants, researchers quantified the gains and losses of different nutrition delivery practices during the transition to enteral feeds.

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Exercise is unrelated to risk of early menopause

The amount of physical activity that women undertake is not linked to their risk of early menopause, according to the largest study ever to investigate this question.

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How weight loss is linked to future health for older adults

A study evaluated information from the Study of Osteoporotic Fractures and looked specifically at health and weight for women who were over age 65. Reviewing more than 20 years' worth of data for study participants, the team of researchers had the chance to examine links between long-term weight gain/loss and health.

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Natural 'breakdown' of chemicals predicts lung damage in 9/11 firefighters

Abnormal levels of more than two dozen metabolites -- chemicals produced in the body as it breaks down fats, proteins and carbohydrates -- can reliably predict which Sept. 11 firefighters developed lung disease and which did not, a new analysis shows.

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Cryptosporidiosis worsened in mice on probiotics

In an unexpected research finding infections with the intestinal parasite, Cryptosporidium parvum, worsened in mice that had been given a probiotic.

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Investigators find that bile acids reduce cocaine reward

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new study.

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Eating in 10-hour window can override disease-causing genetic defects, nurture health

Scientists found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window.

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Growth in first 3 years of life affects respiratory health in children

Children's growth in the first three years of life affects the development of their lungs and the risk of asthma at 10 years of age.

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Novel concepts for the diagnosis of fatty liver and personalized treatment

Almost one in three adults suffer from non-alcoholic fatty liver. For the affected people this increases the risk of complications such as liver cancer, diabetes, high blood pressure and stroke.

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King Bio Issues Voluntary Nationwide Recall of It’s Kids and Infant Products Due to Potential Microbial Contamination

King Bio recalls products due to microbial contamination.

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Living Well Remedies, LLC Issues Voluntary Nationwide Recall of Weight Away Remedy, Lot # 111417LWL614, Due To Microbial Contamination

Living Well Remedies recalls Weight Away Remedy lot# 111417LWL614 due to potential microbial contamination.

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Time-restricted feeding improves health in mice with defective circadian clocks

It turns out timing really is everything, at least when it comes to the diets of lab mice whose circadian clocks are disrupted. A study is reporting that limiting the times when the animals eat can correct obesity and other metabolic problems that are normally seen in these mice, even when they're fed an unhealthy diet. The results suggest a previously unknown link between disruption of the clock and eating behavior.

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Amazonian fruit prevents obesity in overfed mice

An extract of camu camu -- a fruit native to the Amazon -- prevents obesity in mice fed a diet rich in sugar and fat, say researchers. The discovery suggests that camu camu phytochemicals could play a leading role in the fight against obesity and metabolic disease.

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Changes in breakfast and dinner timings can reduce body fat

Modest changes to breakfast and dinner times can reduce body fat, a new pilot study reports.

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Switching to hunter-gatherer lifestyle may increase diversity in children's gut microbes

Immersing city dwellers in the traditional lifestyle and diet of a rainforest village for two weeks increases the diversity of the visiting children's -- but not the adults' -- gut microbiota. In a small pilot study, researchers show that the immersion visit did little to shift the adults' skin, oral, nasal and fecal microbiota.

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Father's diet could affect the long-term health of his offspring

New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring.

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NIH names Dr. Helene Langevin director of the National Center for Complementary and Integrative Health

Helene M. Langevin, M.D., C.M., named director of the National Center for Complementary and Integrative Health (NCCIH).

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Rethinking a healthy diet from a global perspective

Scientists are using research from several large global studies to develop an updated, international approach of identifying a healthy diet.

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The link between obesity, the brain, and genetics

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

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Media Advisory: Lecture to explore the impact of nature on health

Information about an upcoming lecture by Dr. Gregory Bratman titled “Nature Contact and Human Health: A Multimethod Approach.”

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Low carbohydrate diets are unsafe and should be avoided, study suggests

A large study suggests that low carbohydrate diets are unsafe and should be avoided, say researchers who found that people who consumed a low carbohydrate diet were at greater risk of premature death.

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Take a vacation -- it could prolong your life

A 40-year Finnish study of middle-aged male executives finds that taking vacations could prolong life.

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Post-workout muscle building and repair blunted in obese adults

Obesity is associated with a host of health problems, including heart disease, type 2 diabetes and high blood pressure. According to a new study, obesity also diminishes a person's ability to build muscle after engaging in resistance exercise.

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The sugar wars: Rhetoric or reason?

Over the past 50 years researchers, clinicians, professional organizations, and health charities have waged war on sugar, calling for dietary recommendations to be changed and for a sugar tax on soft drinks and sweet treats in an effort to reduce obesity and cardiovascular diseases.

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High-sugar feeding only at active times of day reduces adverse effects in rats

Researchers showed that limiting the consumption of a high-sucrose diet to the nighttime, when rats are most active, alleviated some of its most harmful effects associated with high levels of fat in the blood and liver. This work suggested that temporal controls on sugar intake in humans could also help in the fight against components of metabolic syndrome such as diabetes, obesity, and high blood pressure.

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Diet has bigger impact on emotional well-being in women than in men

Women may need a more nutrient-rich diet to support a positive emotional well-being, according to new research.

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Risk factors for fast-spreading facial gangrene

Noma, a rare disease found predominantly in underserved areas, causes progressive destruction, or gangrene, of the tissues of the face and jaw within just the span of one week. Now, researchers have analyzed 74 cases of noma in northwest Nigeria to pinpoint the risk factors for developing the disease.

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'One weird trick' to cut belly fat? Follow a heart-healthy diet!

Do you wish you could decrease your waistline? Reducing abdominal obesity can lower health risks - but despite claims you may have seen on the Internet, no trending diet can help you specifically eliminate belly fat.

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Increased phosphate intake elevates blood pressure in healthy adults

If more phosphate is consumed with food, blood pressure and pulse rate increase in healthy young adults, according to a new study.

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How sleep loss may contribute to adverse weight gain

One night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans, according to researchers. This may explain how shift work and chronic sleep loss impairs our metabolism and adversely affects our body composition.

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Natural sugar defends against metabolic syndrome, in mice

New research, in mice, indicates that a natural sugar called trehalose blocks glucose from the liver and activates a gene that boosts insulin sensitivity, reducing the chance of developing diabetes. The findings suggest new possibilities for treating metabolic syndrome, a cluster of related conditions that includes obesity, diabetes and fatty liver disease.

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Parents' behavior during playtime may affect toddler's weight later on

Researchers have found that toddlers who had poor self-regulation skills -- the ability to control their behaviors and emotions -- went on to have lower BMIs as preschoolers if their mothers engaged with them during playtime and then helped direct them during clean up.

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How healthy is the American diet? The Healthy Eating Index helps determine the answer

Leading nutrition experts describe and evaluate the latest version of the Healthy Eating Index (HEI), which has been issued to correspond to the 2015-2020 Dietary Guidelines for Americans.

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Found: A destructive mechanism that blocks the brain from knowing when to stop eating

Researchers have uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity: leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal cells in the hypothalamus. This blocks leptin from binding to its receptors. This in turn keeps the neurons from signaling that your stomach is full and you should stop eating.

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Young, healthy people still vulnerable to CVD if their LDL cholesterol is high

A study of more than 36,000 people followed for over two decades revealed that healthy individuals considered 'low-risk' still died from cardiovascular disease if they had high low-density lipoprotein (LDL) cholesterol. Without taking into account other risk factors, people with LDL cholesterol levels in the range of 100-159 mg/dL had a 30 to 40 percent higher risk of cardiovascular disease death.

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Institutional Training Programs for Predoctoral and Postdoctoral Researchers

In this blog post, Dr. Lanay Mudd discusses institutional training programs supported by NCCIH including T32 programs and one T90/R90 program.

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Understanding the Influence of the Experimental Setting on Pain Ratings

In this NCCIH-funded study, researchers suggest the experimental setting influences how study participants assess painful stimuli; these findings may help researchers design studies to better understand the mechanisms involved in chronic pain.

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