Cryptosporidiosis worsened in mice on probiotics

In an unexpected research finding infections with the intestinal parasite, Cryptosporidium parvum, worsened in mice that had been given a probiotic.

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Investigators find that bile acids reduce cocaine reward

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new study.

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Eating in 10-hour window can override disease-causing genetic defects, nurture health

Scientists found that mice lacking the biological clocks thought to be necessary for a healthy metabolism could still be protected against obesity and metabolic diseases by having their daily access to food restricted to a 10-hour window.

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Growth in first 3 years of life affects respiratory health in children

Children's growth in the first three years of life affects the development of their lungs and the risk of asthma at 10 years of age.

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Novel concepts for the diagnosis of fatty liver and personalized treatment

Almost one in three adults suffer from non-alcoholic fatty liver. For the affected people this increases the risk of complications such as liver cancer, diabetes, high blood pressure and stroke.

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King Bio Issues Voluntary Nationwide Recall of It’s Kids and Infant Products Due to Potential Microbial Contamination

King Bio recalls products due to microbial contamination.

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Living Well Remedies, LLC Issues Voluntary Nationwide Recall of Weight Away Remedy, Lot # 111417LWL614, Due To Microbial Contamination

Living Well Remedies recalls Weight Away Remedy lot# 111417LWL614 due to potential microbial contamination.

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Time-restricted feeding improves health in mice with defective circadian clocks

It turns out timing really is everything, at least when it comes to the diets of lab mice whose circadian clocks are disrupted. A study is reporting that limiting the times when the animals eat can correct obesity and other metabolic problems that are normally seen in these mice, even when they're fed an unhealthy diet. The results suggest a previously unknown link between disruption of the clock and eating behavior.

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Amazonian fruit prevents obesity in overfed mice

An extract of camu camu -- a fruit native to the Amazon -- prevents obesity in mice fed a diet rich in sugar and fat, say researchers. The discovery suggests that camu camu phytochemicals could play a leading role in the fight against obesity and metabolic disease.

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Changes in breakfast and dinner timings can reduce body fat

Modest changes to breakfast and dinner times can reduce body fat, a new pilot study reports.

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Switching to hunter-gatherer lifestyle may increase diversity in children's gut microbes

Immersing city dwellers in the traditional lifestyle and diet of a rainforest village for two weeks increases the diversity of the visiting children's -- but not the adults' -- gut microbiota. In a small pilot study, researchers show that the immersion visit did little to shift the adults' skin, oral, nasal and fecal microbiota.

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Father's diet could affect the long-term health of his offspring

New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring.

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NIH names Dr. Helene Langevin director of the National Center for Complementary and Integrative Health

Helene M. Langevin, M.D., C.M., named director of the National Center for Complementary and Integrative Health (NCCIH).

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Rethinking a healthy diet from a global perspective

Scientists are using research from several large global studies to develop an updated, international approach of identifying a healthy diet.

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The link between obesity, the brain, and genetics

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

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Media Advisory: Lecture to explore the impact of nature on health

Information about an upcoming lecture by Dr. Gregory Bratman titled “Nature Contact and Human Health: A Multimethod Approach.”

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Low carbohydrate diets are unsafe and should be avoided, study suggests

A large study suggests that low carbohydrate diets are unsafe and should be avoided, say researchers who found that people who consumed a low carbohydrate diet were at greater risk of premature death.

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Take a vacation -- it could prolong your life

A 40-year Finnish study of middle-aged male executives finds that taking vacations could prolong life.

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Post-workout muscle building and repair blunted in obese adults

Obesity is associated with a host of health problems, including heart disease, type 2 diabetes and high blood pressure. According to a new study, obesity also diminishes a person's ability to build muscle after engaging in resistance exercise.

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The sugar wars: Rhetoric or reason?

Over the past 50 years researchers, clinicians, professional organizations, and health charities have waged war on sugar, calling for dietary recommendations to be changed and for a sugar tax on soft drinks and sweet treats in an effort to reduce obesity and cardiovascular diseases.

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High-sugar feeding only at active times of day reduces adverse effects in rats

Researchers showed that limiting the consumption of a high-sucrose diet to the nighttime, when rats are most active, alleviated some of its most harmful effects associated with high levels of fat in the blood and liver. This work suggested that temporal controls on sugar intake in humans could also help in the fight against components of metabolic syndrome such as diabetes, obesity, and high blood pressure.

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Diet has bigger impact on emotional well-being in women than in men

Women may need a more nutrient-rich diet to support a positive emotional well-being, according to new research.

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Risk factors for fast-spreading facial gangrene

Noma, a rare disease found predominantly in underserved areas, causes progressive destruction, or gangrene, of the tissues of the face and jaw within just the span of one week. Now, researchers have analyzed 74 cases of noma in northwest Nigeria to pinpoint the risk factors for developing the disease.

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'One weird trick' to cut belly fat? Follow a heart-healthy diet!

Do you wish you could decrease your waistline? Reducing abdominal obesity can lower health risks - but despite claims you may have seen on the Internet, no trending diet can help you specifically eliminate belly fat.

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Increased phosphate intake elevates blood pressure in healthy adults

If more phosphate is consumed with food, blood pressure and pulse rate increase in healthy young adults, according to a new study.

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How sleep loss may contribute to adverse weight gain

One night of sleep loss has a tissue-specific impact on the regulation of gene expression and metabolism in humans, according to researchers. This may explain how shift work and chronic sleep loss impairs our metabolism and adversely affects our body composition.

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Natural sugar defends against metabolic syndrome, in mice

New research, in mice, indicates that a natural sugar called trehalose blocks glucose from the liver and activates a gene that boosts insulin sensitivity, reducing the chance of developing diabetes. The findings suggest new possibilities for treating metabolic syndrome, a cluster of related conditions that includes obesity, diabetes and fatty liver disease.

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Parents' behavior during playtime may affect toddler's weight later on

Researchers have found that toddlers who had poor self-regulation skills -- the ability to control their behaviors and emotions -- went on to have lower BMIs as preschoolers if their mothers engaged with them during playtime and then helped direct them during clean up.

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How healthy is the American diet? The Healthy Eating Index helps determine the answer

Leading nutrition experts describe and evaluate the latest version of the Healthy Eating Index (HEI), which has been issued to correspond to the 2015-2020 Dietary Guidelines for Americans.

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Found: A destructive mechanism that blocks the brain from knowing when to stop eating

Researchers have uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity: leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal cells in the hypothalamus. This blocks leptin from binding to its receptors. This in turn keeps the neurons from signaling that your stomach is full and you should stop eating.

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Young, healthy people still vulnerable to CVD if their LDL cholesterol is high

A study of more than 36,000 people followed for over two decades revealed that healthy individuals considered 'low-risk' still died from cardiovascular disease if they had high low-density lipoprotein (LDL) cholesterol. Without taking into account other risk factors, people with LDL cholesterol levels in the range of 100-159 mg/dL had a 30 to 40 percent higher risk of cardiovascular disease death.

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Institutional Training Programs for Predoctoral and Postdoctoral Researchers

In this blog post, Dr. Lanay Mudd discusses institutional training programs supported by NCCIH including T32 programs and one T90/R90 program.

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Understanding the Influence of the Experimental Setting on Pain Ratings

In this NCCIH-funded study, researchers suggest the experimental setting influences how study participants assess painful stimuli; these findings may help researchers design studies to better understand the mechanisms involved in chronic pain.

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Healthy diet linked to healthy cellular aging in women

Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women.

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Institutional Training Programs for Predoctoral and Postdoctoral Researchers

In this blog post, Dr. Lanay Mudd discusses institutional training programs supported by NCCIH including T32 programs and one T90/R90 program.

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Poor sleep and type 2 diabetes means slower wound healing

People with Type 2 diabetes who don't sleep well could need more time to heal their wounds, according to a new study.

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Strawberries could help reduce harmful inflammation in the colon

Inflammatory bowel disease is a set of painful conditions that can cause severe diarrhea and fatigue. Researchers are now reporting that a simple dietary intervention could mitigate colonic inflammation and improve gut health. In this case, a strawberry -- or rather, less than a cupful of strawberries -- a day could help keep the doctor away.

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Saliva could influence taste preferences

Saliva is crucial for tasting and digesting food. But scientists have now found that saliva could also be part of a feedback loop that influences how food tastes to people -- and by extension, what foods they're willing to eat. They hope that, one day, the findings could help consumers stick to a healthier diet.

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Consuming milk at breakfast lowers blood glucose throughout the day

A change in breakfast routine may provide benefits for the management of type 2 diabetes, according to a new study. A team of scientists found that milk consumed with breakfast cereal reduced postprandial blood glucose concentration compared with water, and high dairy protein concentration reduced postprandial blood glucose concentration compared with normal dairy protein concentration. The high-protein treatment also reduced appetite after the second meal compared with the low-protein equivalent.

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More protein after weight loss may reduce fatty liver disease

Increasing the amount of protein in the diet may reduce the liver's fat content and lower the risk of diabetes in people with nonalcoholic fatty liver disease (NAFLD).

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Obesity, infertility and oxidative stress in mouse egg cells

Proteomic analysis of oocytes from obese mice showed changes in a protein that promotes antioxidant production and may alter meiotic spindles.

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Evening preference, lack of sleep associated with higher BMI in people with prediabetes

People with prediabetes who go to bed later, eat meals later and are more active and alert later in the day -- those who have an 'evening preference' -- have higher body mass indices compared with people with prediabetes who do things earlier in the day, or exhibit morning preference.

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Two-Day Workshop to Focus on Strengthening Natural Products Research

In this blog post, Dr. Craig Hopp addresses an upcoming natural products clinical trials workshop scheduled for September 13-14 at NIH in Bethesda, Md.

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World Organix, LLC Issues Voluntary Nationwide Recall of Blissful Remedies Red Maeng Da 100% Mitragyna Speciosa, Blissful Remedies Red Maeng Da Liquid Kratom Mitragyna Speciosa, Blissful Remedies 4 Hour Chill Slow Motion Blend, Due to High Microbial Loads

World Organix LLC recalls products – Blissful Remedies Red Maeng Da 100% Mitragyna Speciosa capsules, Blissful Remedies Red Maeng Da Liquid Kratom Mitragyna Speciosa, Blissful Remedies 4 Hour Chill Slow Motion Blend.

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Zakah Life Recalls Kratom Because Of Possible Health Risk

Zakah Life recalls kratom products because of potential Salmonella contamination.

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Moderate carbohydrate intake may be best for health, study suggests

A new study has found that diets both low and high in carbohydrates were linked with an increase in mortality, while moderate consumers of carbohydrates had the lowest risk of mortality. The study also found that low-carb diets that replace carbohydrates with proteins and fats from plant sources were associated with lower risk of mortality compared to those that replace carbohydrates with proteins and fat from animal sources.

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Using mushrooms as a prebiotic may help improve glucose regulation

Eating white button mushrooms can create subtle shifts in the microbial community in the gut, which could improve the regulation of glucose in the liver, according to a team of researchers. They also suggest that better understanding this connection between mushrooms and gut microbes in mice could one day pave the way for new diabetes treatments and prevention strategies for people.

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Exploring Pediatric Research at the Recent Advisory Council Meeting

In this blog post, acting NCCIH deputy director Dr. Wendy Weber discusses information shared at a recent NCCIH mini-symposium, “Pediatric Complementary and Integrative Health.”

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Healthy fat cells uncouple obesity from diabetes

Researchers have identified possible ways to uncouple obesity from co-morbidities such as heart disease and insulin resistance.

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It's possible to reverse damage caused by aging cells

What's the secret to aging well? Researchers have answered it -- on a cellular level.

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Eating breakfast burns more carbs during exercise and accelerates metabolism for next meal

New research suggests that eating breakfast could 'prime' the body to burn carbohydrates during exercise and more rapidly metabolize foods after working out.

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Chemicals found in vegetables prevent colon cancer in mice

Chemicals produced by vegetables such as kale, cabbage and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study shows.

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Weight loss: Surprising scale of health benefits for biggest losers

When it comes to shedding pounds, it pays to think big, according to new research.

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Scientists propose a new lead for Alzheimer's research

Scientists have suggested a potential link between iron in our cells and the rare gene mutations that cause Alzheimer's disease, which could provide new avenues for future research.

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Policy changes can help ease roadblocks to a healthy diet

Diet modification can be a vital step to prevent cardiovascular disease. While various biological, economical, physical, social and psychological factors influence food choices, interventions targeting these factors can lead to meaningful improvements in long-term eating habits.

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Wearable devices and mobile health technology: One step towards better health

With increasing efforts being made to address the current global obesity epidemic, wearable devices and mobile health ('mHealth') technology have emerged as promising tools for promoting physical activity. However, current literature seems to indicate that these new technologies may serve best as part of a larger overall health plan, rather than working alone to encourage weight loss.

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Thirty percent increase in risk of fracture after gastric bypass

A study shows that the risk of fractures increases by about 30 percent after a gastric bypass operation. It was also discovered that falls increase after these operations.

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Grip strength of children gives clues about their future health

Adolescents with a strong hand grip -- an indicator of overall muscle strength -- have better odds of being healthy over time, according to a two-year study of 368 elementary school children. The findings give insights to identify youngsters at future risk for developing diabetes and cardiovascular disease.

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Making weight: Ensuring that micro preemies gain pounds and inches

A quality-improvement project to standardize feeding practices for micro preemies helped to boost their weight and nearly quadrupled the frequency of lactation consultations ordered in the neonatal intensive care unit, a multidisciplinary team finds.

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A diverse diet may not be the healthiest one

Scientific evidence to date does not support the notion that eating a diverse diet is healthy or promotes a healthy weight. Some studies suggest that a diverse diet may increase food consumption and the prevalence of obesity.

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Fat-blocking effect of nanofibers discovered

Tiny balls of nano-sized cellulose fibers added to food reduced fat absorption by up to half in laboratory and animal experiments, scientists report.

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Dietary carbohydrates could lead to osteoarthritis, new study finds

Researchers have found that carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice -- even when the animals didn't differ in weight.

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Bribing bacteria to play nicely is good for everyone

Researchers report that giving mice dietary iron supplements enabled them to survive a normally lethal bacterial infection and resulted in later generations of those bacteria being less virulent. The approach demonstrates in preclinical studies that non-antibiotic-based strategies -- such as nutritional interventions -- can shift the relationship between the patient and pathogens away from antagonism and toward cooperation.

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Prevalence and Profile of High Impact Chronic Pain

Almost 11 million U.S. adults have “High Impact Chronic Pain”—that is, pain that has lasted 3 months or longer and is accompanied by at least one major activity restriction, such as being unable to work outside the home, go to school, or do household chores.

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Women and men experience different benefits from low-calorie diets

A low-calorie diet causes different metabolic effects in women than in men, a new study suggests.

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Soy diets might increase women's bone strength

Researchers now have discovered through a new animal study that soy protein found in food might counter the negative effects of menopause on bone and metabolic health. Moreover, the researchers believe that soy protein might also have positive impacts on bone strength for women who have not yet reached menopause.

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Got the 'drunchies'? New study shows how heavy drinking affects diet

After seeing an ad in a campus newspaper promoting unhealthy late-night foods, researchers decided to look at a sample of college students to better understand how drinking affects what they eat.

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US teens: Higher prevalence of obesity than Grenada youth

Medical researchers have found a lower prevalence of overweight and obesity among youth in Grenada compared to US adolescents. The differences may reflect the impact of the westernized diet and lifestyle. The research may lead to a change in worldwide obesity prevention strategy.

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Low-protein diet during pregnancy increases prostate cancer risk in offspring, rat study shows

Experiments with rats show that intrauterine protein restriction induces sex hormone imbalance, which appears to favor development of cancer in old age. The rate of prostate tumor development reached 50 percent among the old rats submitted to low-protein diet during pregnancy and lactation alike.

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Insulin resistance under-diagnosed in non-diabetics with Parkinson's disease

Almost two-thirds of non-diabetic patients with Parkinson's disease (PD) may be insulin resistant, despite having normal blood sugar, report scientists. Their findings suggest that insulin resistance in PD is a common and largely undetected problem, especially in patients who are overweight.

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Eating crickets can be good for your gut, according to new clinical trial

A new clinical trial shows that consuming crickets can help support the growth of beneficial gut bacteria and that eating crickets is not only safe at high doses but may also reduce inflammation in the body.

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Cystic fibrosis impacts growth in the womb, research shows

New research has shown that babies with cystic fibrosis are born weighing less than babies without the condition, even allowing that they are more likely to be born prematurely.

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Blocking digestive hormone may prevent diet-induced pancreatic cancer

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking CCK may help prevent the spread of pancreatic tumors to other areas of the body (metastases).

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Why weight loss produces remission of type 2 diabetes in some patients

A clinical trial recently showed that nearly half of individuals with type 2 diabetes achieved remission to a non-diabetic state after a weight-loss intervention delivered within six years of diagnosis. Now a new study eveals that this successful response to weight loss is associated with the early and sustained improvement in the functioning of pancreatic beta cells.

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Makeup of an individual's gut bacteria may play role in weight loss

A preliminary study suggests that, for some people, specific activities of gut bacteria may be responsible for their inability to lose weight, despite adherence to strict diet and exercise regimens.

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Innovative technique converts white fat to brown fat

Increasing healthy brown fat might help weight management and reduce symptoms of diabetes. Engineers have developed a simple, innovative method to directly convert white fat to brown fat outside the body and then reimplant it in a patient. The technique uses fat-grafting procedures commonly performed by plastic surgeons, in which fat is harvested from under the skin and then retransplanted into the same patient for cosmetic or reconstructive purposes.

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Measure of belly fat in older adults is linked with cognitive impairment

Data from over 5,000 adults over the age of 60 indicates that as waist:hip ratio increases, so does cognitive impairment. The findings have significant implications as the global prevalence of dementia is predicted to increase from 24.3 million in 2001 to 81.1 million by 2040.

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