Exercise is more critical than diet to maintain weight loss

The study showed successful weight-loss maintainers rely on physical activity to remain in energy balance (rather than chronic restriction of dietary intake) to avoid weight regain. Successful weight-loss maintainers are individuals who maintain a reduced body weight of 30 pounds or more for over a year. The study, published in the March issue of Obesity, was selected as the Editor's Choice article.

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Omega-3 and omega-6 fatty acids may play opposite roles in childhood asthma

Dietary intake of two fatty acids, omega-3 and omega-6, may have opposite effects on the severity of asthma in children and may also play opposite roles in modifying their response to indoor air pollution, according to new research.

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Maternal diet during pregnancy may modulate the risk of ADHD symptoms in children

A study suggest that the risk of a child developing symptoms of attention deficit hyperactivity disorder (ADHD) may be modulated by the mother's diet during pregnancy. The research analyzed samples of umbilical cord plasma to quantify the levels of omega-6 and omega-3 that reach the fetus. The analysis showed a higher omega-6:omega-3 ratio to be associated with a higher risk of ADHD symptoms at seven years of age.

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Offspring of older mothers are more responsive to aging interventions

Maternal age affects how well offspring respond to dietary interventions that are known to increase lifespan, scientists report in a rotifer study.

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Fact or Fiction: What to Know About Smoking Cessation and Medications

Tobacco use is the leading preventable cause of death in the United States, resulting in more than 480,000 deaths annually. Almost 70 percent of current smokers report wanting to quit smoking, but quitting can be hard and often takes multiple attempts. A variety of FDA-approved medications are available to help people successfully quit smoking.

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Gene transfer improves diabetes-linked heart ailment

Researchers have shown that a gene transfer technique can combat heart dysfunction caused by diabetes.

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On the keto diet? Ditch the cheat day

The often embraced 'cheat day' is a common theme in many diets and the popular ketogenic diet is no exception. But new research says that just one 75-gram dose of glucose -- the equivalent a large bottle of soda or a plate of fries -- while on a high fat, low carbohydrate diet can lead to damaged blood vessels.

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Smartphone app detects diet cheat

According to a recent study, a first-of-its-kind smartphone app called OnTrack can predict ahead of time when users are likely to lapse in their weight loss plan and help them stay on track.

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Eating small amounts of red and processed meats may increase risk of early death

A new study suggests that eating red and processed meats -- even in small amounts -- may increase the risk of death from all causes, especially cardiovascular disease.

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Mammography: What You Need to Know

Mammograms are still the best primary tool for breast cancer screening. To continue to protect women's health, the FDA is proposing updates to the mammography regulations to reflect advances in mammography technology and processes.

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Testosterone can help men with hypogonadism lose weight, keep it off

Long-term testosterone therapy can help men with hypogonadism lose weight and maintain their weight loss, researchers report.

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Tuck into colourful fruits and vegetables and see the light

A $5.7 billion global medical bill to restore sight for the estimated 45 million people with cataracts could be slashed in half by a diet rich in colourful fruits and vegetables, according to an international study.

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Detrimental effect of overlooking female athletes' nutritional needs

As poor nutrition can negatively affect everything from bone to reproductive health, more attention needs to be paid to the specific nutritional needs of female athletes, researchers argue.

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Kingston Pharma, LLC RECALLS " DG™/health NATURALS baby Cough Syrup + Mucus” Because of Possible Health Risk

Kingston Pharma, LLC recalls Lot KL180157 of its 2-fluid ounce (59 mL) bottles of DG™/health NATURALS baby Cough Syrup + Mucus” because it has the potential to be contaminated with Bacillus cereus/ Bacillus circulans.

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Obesity speeds up the start of puberty in boys

Girls are not the only ones who go through puberty early if they have obesity. Boys with obesity enter puberty at an earlier age than average, according to a new study.

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Investigational obesity drug, oxytocin, weakens brain's reward signals for food

The hormone oxytocin reduces the communication between different brain areas involved in the cognitive, sensory and emotional processing of food cues that people with obesity demonstrate when they look at high-calorie foods.

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Adipose hormone may play role in obesity-related asthma

New research suggests a hormone released from fat tissue is critical in the development of obesity-related asthma and may be a target of future treatments for the disease.

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Chemicals in household dust may promote fat cell development

Endocrine-disrupting chemicals present in household dust promote the development of fat cells in a cell model and could contribute to increased growth in children relative to their age.

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Generic weight-loss drug may be safe and effective for long-term treatment

An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a new study.

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For migraine sufferers with obesity, losing weight can decrease headaches

For migraine sufferers with obesity, losing weight can decrease headaches and improve quality of life, researchers report.

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Eating later in the day may be associated with obesity

Eating later in the day may contribute to weight gain, according to a new study.

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Improved PCOS symptoms correlate with gut bacterial composition

Symptoms of polycystic ovary syndrome (PCOS) improved with exposure to healthy bacteria in the gut, according to a study in a mouse model of this common women's endocrine disorder.

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In healthy young women, sleep quality varies throughout the menstrual cycle

Young women are more likely to experience sleep disruption in the days leading up to their menstrual period, according to a new study.

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Obese mouse mothers trigger heart problems in offspring

Mitochondria manufacture energy in every cell of the body, including heart muscle cells. A new study shows that cardiac mitochondria are abnormal in the offspring of mouse mothers that become obese due to a high-fat, high sugar diet. Those offspring then pass on the mitochondrial defects at least two more generations.

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Sleep problems during pregnancy affect glucose, may increase risk of childhood obesity

The study found that mild sleep apnea changed sugar levels during pregnancy and was connected to infant growth patterns related to increased risk of obesity.

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Study in mice examines impact of reused cooking oil on breast cancer progression

Compounds in thermally abused cooking oils may trigger genetic, biochemical changes that hasten the progression of late-stage breast cancer, promoting tumor cells' growth and proliferation.

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Study links perimenopause to accelerated fat mass gains, lean mass losses

A new study confirms what women approaching menopause have long suspected: menopause does make fat go up. The study finds that women undergoing perimenopause lost lean body mass and more than doubled their fat mass. The research demonstrates that body mass index (BMI) is a very important clinical tool for predicting health events, such as getting diabetes or having cardiovascular disease -- but is a less useful gauge of cardio-metabolic risk in older women.

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No evidence that calcium increases risk of AMD

Eating a calcium-rich diet or taking calcium supplements does not appear to increase the risk of age-related macular degeneration (AMD), according to the findings of a study by scientists at the National Eye Institute (NEI). AMD is a leading cause of vision loss and blindness among people age 65 and older in the United States. The study findings are published in JAMA Ophthalmology.

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BMI, but not age at puberty, tied to risk of multiple sclerosis

Some studies have suggested that people who are younger when they enter puberty are more likely to later develop multiple sclerosis (MS). But a new study attributes that link to body mass index (BMI).

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Modeled Manual Therapy May Protect Against Repetitive Motion Pain, Rat Study Suggests

Results of a recently published rat study suggest that 3 weeks of modeled manual therapy (MMT) largely prevented the physiological processes and pain that often accompany a repetitive motion injury.

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Generic advice doesn't help patients drop pounds

When it comes to losing weight, doctors' messages to their patients can make a powerful difference, according to new research.

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FTC & FDA issue warning letters to supplement sellers

Ads abound for products that claim to treat or prevent serious health conditions. Unfortunately, these products often are unproven and useless. Sometimes the ads even make false promises for Alzheimer’s disease and dementia – conditions for which science has no cure.

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Prescribing healthy food in Medicare/Medicaid is cost effective, could improve health

A team of researchers modeled the health and economic effects of healthy food prescriptions in Medicare and Medicaid. The study finds that health insurance coverage to offset the cost of healthy food for Medicare and/or Medicaid participants would be highly cost effective after five years and improve health outcomes.

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NCCIH Activities at the 2019 American Pain Society (APS) Scientific Meeting

In this blog post Dr. Emmeline Edwards discusses planned NCCIH activities around the 2019 American Pain Society Scientific Meeting In Milwaukee, WI between April 3 & April 6, 2019.

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Eating fish may help prevent asthma

An innovative study has revealed new evidence that eating fish can help prevent asthma.

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Healthy fats improve nerve function in obese mice

Swapping dietary saturated fats for monounsaturated fats reverses nerve damage and restores nerve function in male mice, finds new preclinical research. These data support further investigation of diets rich in healthy fats as a potential treatment for the nerve damage that occurs with diabetes, known as diabetic neuropathy.

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ACC/AHA guidance for preventing heart disease, stroke released

Adopting a heart healthy eating plan, getting more exercise, avoiding tobacco and managing known risk factors are among the key recommendations in the 2019 Primary Prevention of Cardiovascular Disease guideline from the American College of Cardiology (ACC) and the American Heart Association (AHA). Also, it is recommended that aspirin should only rarely be used to help prevent heart attacks and stroke in people without known cardiovascular disease.

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How Many Calories? Keep an Eye on the Menu

FDA's final rule on menu labeling gives consumers the information on calories they need to make informed food choices.

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Higher consumption of sugary beverages linked with increased risk of early mortality

The more sugar-sweetened beverages (SSBs) people consumed, the greater their risk of premature death--particularly death from cardiovascular disease, and to a lesser extent from cancer, according to a large long-term study of US men and women. The risk of early death linked with drinking SSBs was more pronounced among women.

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Higher egg and cholesterol consumption hikes heart disease and early death risk

Cancel the cheese omelet. A large, new study of nearly 30,000 people reports adults who ate more eggs and dietary cholesterol had a significantly higher risk of cardiovascular disease and death from any cause. People need to consume lower amounts of cholesterol to have a lower risk of heart disease, the study authors said.

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Free fatty acids appear to rewire cells to promote obesity-related breast cancer

Free fatty acids in the blood are linked with higher rates of estrogen-receptor positive breast cancer in obese postmenopausal women, according to a new study.

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Green tea cuts obesity, health risks in mice

Green tea cut obesity and a number of inflammatory biomarkers linked with poor health in a new study.

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Danger of vitamin B12 deficiency

Using roundworms, one of Earth's simplest animals, bioscientists have found the first direct link between a diet containing too little vitamin B12 and an increased risk of infection by two potentially deadly pathogens.

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Moderate muscle strength may lower risk for type 2 diabetes

Of the 30 million Americans with diabetes, 90 to 95 percent have type 2, according to the Centers for Disease Control and Prevention. New research shows building muscle strength may lower risk for the disease by 32 percent.

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New 'tracers' improve diagnosis of cancer and may be useful for treatment

Researchers have identified two new nuclear medicine tracers that make it easier to diagnose and potentially treat multiple types of cancer, providing high-quality images with less patient preparation and shorter acquisition times.

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Media Advisory: NIH to host a spring lecture series on the gut microbiome

“Microbes in Our Gut: Emerging Insights on Health and Disease” is the theme of three special lectures in spring 2019 sponsored by the National Center for Complementary and Integrative Health (NCCIH), part of the National Institutes of Health.

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Yo-yo dieting may increase women's heart disease risk

Women who have lost at least 10 pounds, only to regain the weight within a year, are more likely to have a poor score on the American Heart Association's -- Life's Simple 7, a measure of how well people control important heart disease risk factors. The more episodes of yo-yo dieting women report, the worse they score on Life's Simple 7. In addition to achieving a healthy weight, maintaining a consistent body weight may be important for lowering heart disease risk.

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Diet may be a key factor for Influenza A virus exposure in wild African mammals

Given the importance and wide distribution of Influenza A viruses, it is surprising how little is known about infections of wild mammals. A new study sheds light on which species are commonly infected and why.

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Fasting-mimicking diet holds promise for treating people with inflammatory bowel disease

Fasting-mimicking diet holds promise for treating people with inflammatory bowel disease, a new study finds. A clinical trial shows reduction of inflammation in humans and in mice, the diet appears to reverse Crohn's and colitis pathology.

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Want a healthy heart? Turn off the TV and eat a good breakfast

The small lifestyle choices we make each day add up when it comes to heart health. In a new two-pronged study, people who spent less time watching TV and regularly ate an energy-rich breakfast showed significantly less plaque and stiffness in their arteries, indicating a lower chance of developing heart disease or suffering a stroke.

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Daily intake of nutritional supplements cannot prevent depression

The largest randomized clinical trial to study the effects of nutritional strategies on the prevention of major depressive disorder concludes that daily intake of nutritional supplements cannot prevent depression.

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Scientists identify genetic factors that may cause some people to become obese

New research on leptin, a hormone that regulates appetite, reveals a previously unknown mechanism that may be responsible for at least 10 percent of obesity cases. The findings could help identify individuals with treatable forms of the condition.

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Most microbes in hummingbird feeders do not pose health hazard

A new study is one of the first to address the potential for sugar water from hummingbird feeders to act as a vector for avian -- or even zoonotic -- pathogens. It found that the majority of microbes growing in feeders do not likely pose a significant health hazard to birds or humans.

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Eating healthy on a limited budget is possible, researchers find

A new study found that with menu planning and access to stores selling items in bulk, the average daily cost for serving healthy meals to a family of four was $25 in 2010 dollars. This cost was consistent with the US Department of Agriculture (USDA) low-income cost of food meal plan, but higher than the cost of the USDA Thrifty Food Plan.

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Mediterranean diet boosts endurance exercise within days, study finds

Researchers have found that eating a Mediterranean diet can improve athletes' endurance exercise performance after just four days.

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Alzheimer's-like symptoms reversed in mice

A diet containing compounds found in green tea and carrots reversed Alzheimer's-like symptoms in mice genetically programmed to develop the disease.

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Low-carb diet tied to common heart rhythm disorder

Low-carb diets are all the rage, but can cutting carbohydrates spell trouble for your heart? People getting a low proportion of their daily calories from carbohydrates such as grains, fruits and starchy vegetables are significantly more likely to develop atrial fibrillation (AFib), the most common heart rhythm disorder, according to a new study.

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Gaining a little weight after quitting tobacco is offset by the benefits for people with diabetes

People with diabetes who quit smoking tobacco may have a lower risk of heart attacks, strokes and other cardiovascular diseases -- and weight gain following smoking cessation does not mitigate the health benefits among these patients, according to one study. Long-term, heavy smoking is a risk factor for cognitive decline, researchers found in an unrelated study.

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More immediate concerns beat heart health in the priorities and behaviors of young women

Although it is the leading cause of death in women, more than 75 percent of young women worry little or not at all about getting heart disease. Most young adult women have taken some actions to preserve their health, such as seeing a doctor, exercising or trying to reduce stress. Competing health concerns and a lack of awareness of heart disease as a killer of women are barriers to young women adopting heart-healthy actions that can reduce their heart disease risk later in life.

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Soda, sugar-sweetened beverages linked to more severe symptoms for people with multiple sclerosis

For people with multiple sclerosis (MS), drinking around 290 calories per day of soda or other sugar-sweetened beverages, or the equivalent of about two cans of non-diet soda, may be tied to more severe symptoms and a higher level of disability compared to people with MS who seldom consume sugar-sweetened beverages, according to a preliminary study.

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Integrated therapy treating obesity and depression is effective

An intervention combining behavioral weight loss treatment and problem-solving therapy with as-needed antidepressant medication for participants with co-occurring obesity and depression improved weight loss and depressive symptoms compared with routine physician care.

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High levels of potentially harmful bacteria found in raw meat dog food products: study

Many raw meat dog food products contain high levels of bacteria that pose potential health risks to both animals and people, finds new research.

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NCCIH Lecture Series Will Explore Gut Microbiome

This blog post announces NCCIH’s Integrative Medicine Research Lecture Series. Dr. Sean Brady kicks it off on March 14, 2019, at 11:00 a.m. with a talk on “Microbes in Our Gut: Emerging Insights on Health and Disease” on the NIH campus in Bethesda, MD. Other speakers follow May 9 and June 10.

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Sunstone Organics Issues Voluntary Nationwide Recall of Select Kratom Products Due to Potential Contamination by Salmonella

Sunstone Organics is voluntarily recalling two lots of Sunstone Organics Kratom due to salmonella contamination.

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Join Us in April for an NIH Blueprint for Neuroscience Research Workshop: The Science of Interoception and Its Roles in Nervous System Disorders

In this blog post, Dr. Wen Chen invites readers to attend the inaugural NIH workshop on “The Science of Interoception and Its Roles in Nervous System Disorders” on April 16 and 17, 2019, on the NIH Campus in Bethesda, Maryland.

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How celastrol sensitizes brains to leptin, curbing hunger and obesity

Celastrol's potent anti-obesity effects were widely reported in 2015. Derived from the roots of the thunder god vine, the drug curbed food intake in obese mice by nearly 80 percent, producing up to a 45 percent weight loss.

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Genetics May Be a Factor in African-American Cigarette Preferences

New NCCIH-funded research suggests genetic factors drive African American preference for mentholated cigarettes.

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Talking to NCCIH Program Staff Can Be Beneficial

In this blog post, NCCIH’s outreach communications program manager Anita McRae-Williams discusses how to engage with Division of Extramural Research (DER) program staff.

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Genetics May Be a Factor in African-American Cigarette Preferences

New NCCIH-funded research suggests genetic factors drive African American preference for mentholated cigarettes.

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High-fat diet and age alter microflora and cause inflammation in heart failure

Growing older and a high-fat diet enriched with omega 6 fatty acids are major contributors to health risks ranging from diabetes to heart failure. How these factors regulate the immune response is now described -- a calorie-dense, obesity-generating diet in aging mice disrupts the composition of the gut microbiome. This correlates with development of a system-wide nonresolving inflammation in acute heart failure, with a notable disruption of the immune cell profile, primarily the neutrophil-leukocyte ratio.

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FDA's Critical Role in Ensuring Supply of Influenza Vaccine

Making the flu vaccine is a highly complex process. The FDA encourages the development of new technologies for producing flu vaccines and plays an important role in making sure safe and effective vaccines are available each flu season.

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